7VYR

Crystal structure of SARS-CoV-2 Spike RBD in complex with the D27 neutralizing antibody Fab fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (H, A)	D27 heavy chain	polymer	252	27037.1	2		Homo sapiens
2	B, E (L, B)	D27 light chain	polymer	238	26123.1	2		Homo sapiens
3	C, F (R, C)	Spike protein S1	polymer	262	29265.2	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
4	G, H, I, J, K... (H, L, R, A, B...)	water	water		18.0	460	Chemie (HOH)

Sequence modifications

R, C: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Met 280	-	initiating methionine
Val 281	-	expression tag
Leu 282	-	expression tag
Val 283	-	expression tag
Asn 284	-	expression tag
Gln 285	-	expression tag
Ser 286	-	expression tag
His 287	-	expression tag
Gln 288	-	expression tag
Gly 289	-	expression tag
Phe 290	-	expression tag
Asn 291	-	expression tag
Lys 292	-	expression tag
Glu 293	-	expression tag
His 294	-	expression tag
Thr 295	-	expression tag
Ser 296	-	expression tag
Lys 297	-	expression tag
Met 298	-	expression tag
Val 299	-	expression tag
Ser 300	-	expression tag
Ala 301	-	expression tag
Ile 302	-	expression tag
Val 303	-	expression tag
Leu 304	-	expression tag
Tyr 305	-	expression tag
Val 306	-	expression tag
Leu 307	-	expression tag
Leu 308	-	expression tag
Ala 309	-	expression tag
Ala 310	-	expression tag
Ala 311	-	expression tag
Ala 312	-	expression tag
His 313	-	expression tag
Ser 314	-	expression tag
Ala 315	-	expression tag
Phe 316	-	expression tag
Ala 317	-	expression tag
Ala 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	164850.7
All*	Total formula weight	164850.7

*Water molecules are not included.