8EZ3

Structure of 3A10 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase

Summary for 8EZ3

Entry DOI	10.2210/pdb8ez3/pdb
EMDB information	28728
Descriptor	Heavy chain of influenza virus neuraminidase antibody 3A10, Light chain of influenza virus neuraminidase antibody 3A10, Neuraminidase, ... (6 entities in total)
Functional Keywords	antibody, neuraminidase, influenza, hydrolase-immune system complex, hydrolase/immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	69844.05
Authors	Mou, Z.,Lei, R.,Wu, N.C.,Dai, X. (deposition date: 2022-10-31, release date: 2023-11-08, Last modification date: 2024-05-01)
Primary citation	Lei, R.,Kim, W.,Lv, H.,Mou, Z.,Scherm, M.J.,Schmitz, A.J.,Turner, J.S.,Tan, T.J.C.,Wang, Y.,Ouyang, W.O.,Liang, W.,Rivera-Cardona, J.,Teo, C.,Graham, C.S.,Brooke, C.B.,Presti, R.M.,Mok, C.K.P.,Krammer, F.,Dai, X.,Ellebedy, A.H.,Wu, N.C. Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase. Immunity, 56:2621-, 2023 Cited by PubMed: 37967533 DOI: 10.1016/j.immuni.2023.10.005 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation