PDB: 5434 件ウェブページステータス検索Chemie searchBIRD

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3LAU	Crystal Structure of Aurora2 kinase in complex with a GSK3beta inhibitor 分子名称: N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide, Serine/threonine-protein kinase 6 著者 Maignan, S, Guilloteau, J.P, Pouzieux, S. 登録日 2010-01-07 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
7N5S	ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6) 分子名称: DNA Strand I, DNA Strand II, ZINC ION, ... 著者 Horton, J.R, Ren, R, Cheng, X. 登録日 2021-06-06 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
2YLM	Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase. 分子名称: CHLORIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 著者 Faesen, A.C, Perrakis, A, Sixma, T.K. 登録日 2011-06-03 公開日 2011-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase Mol.Cell, 44, 2011
7N5T	ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5) 分子名称: DNA Strand I, DNA Strand II, ZINC ION, ... 著者 Horton, J.R, Ren, R, Cheng, X. 登録日 2021-06-06 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
3EI2	Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex 分子名称: 5'-D(*DAP*DAP*DAP*DTP*DGP*DAP*DAP*DTP*(3DR)P*DAP*DAP*DGP*DCP*DAP*DGP*DG)-3', 5'-D(*DCP*DCP*DTP*DGP*DCP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DTP*DT)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
7SFZ	Crystal structure of Mis18a-yippee domain 分子名称: Protein Mis18-alpha, SULFATE ION, ZINC ION 著者 Park, S.H, Cho, U. 登録日 2021-10-04 公開日 2022-10-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Structural Basis for Mis18 Complex Assembly: Implications for Centromere Maintenance To Be Published
3EMH	Structural basis of WDR5-MLL interaction 分子名称: Mixed-lineage leukemia protein 1, SULFATE ION, WD repeat-containing protein 5 著者 Song, J.J, Kingston, R.E. 登録日 2008-09-24 公開日 2008-10-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket. J.Biol.Chem., 283, 2008
2YU2	Crystal structure of hJHDM1A without a-ketoglutarate 分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1A 著者 Han, Z. 登録日 2007-04-05 公開日 2007-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for histone demethylation by JHDM1 To be Published
2YU1	Crystal structure of hJHDM1A complexed with a-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1A 著者 Han, Z. 登録日 2007-04-05 公開日 2007-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for histone demethylation by JHDM1 To be Published
4XF2	Tetragonal structure of Arp2/3 complex 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Jurgenson, C.T, Pollard, T.P. 登録日 2014-12-25 公開日 2015-11-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Crystals of the Arp2/3 complex in two new space groups with structural information about actin-related protein 2 and potential WASP binding sites. Acta Crystallogr.,Sect.F, 71, 2015
4XEG	Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... 著者 Pozharski, E, Malik, S.S, Drohat, A.C. 登録日 2014-12-23 公開日 2015-09-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
3EJL	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-09-18 公開日 2010-03-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010
2YTC	Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22 分子名称: Pre-mRNA-splicing factor RBM22 著者 Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-05 公開日 2007-10-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22 To be Published
7S3P	BD2 domain of human BRD3 bound to Physachenolide C 分子名称: Bromodomain-containing protein 3, CHLORIDE ION, Physachenolide C 著者 Horton, N.C, Chapman, E, Sivinski, J, Zerio, C, Ghadirian, N. 登録日 2021-09-07 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Physachenolide C is a Potent, Selective BET Inhibitor. J.Med.Chem., 66, 2023
3EI1	Structure of hsDDB1-drDDB2 bound to a 14 bp 6-4 photoproduct containing DNA-duplex 分子名称: 5'-D(*DAP*DCP*DGP*DCP*DGP*DAP*(64T)P*(5PY)P*DGP*DCP*DGP*DCP*DCP*DC)-3', 5'-D(*DTP*DGP*DGP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DCP*DGP*DCP*DG)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
2YQD	Solution structure of the fifth bromodomain from mouse polybromo-1 分子名称: POLYBROMO-1 著者 Sano, R, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2007-10-02 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the fifth bromodomain from mouse polybromo-1 To be Published
4XHU	The complex structure of Timeless_PAB and PARP-1_catalytic domain 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Xie, S, Qian, C. 登録日 2015-01-06 公開日 2015-09-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.089 Å) 主引用文献 Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair. Mol.Cell, 60, 2015
7N1R	A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP 分子名称: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... 著者 Yang, J, Musayev, F, Liu, Q. 登録日 2021-05-28 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
2YUF	Solution structure of the NCD2 domain in human transcriptional repressor Nab1 protein 分子名称: NGFI-A-binding protein 1 著者 Saito, K, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-06 公開日 2008-04-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the NCD2 domain in human transcriptional repressor Nab1 protein To be Published
3EF9	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: SULFATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-09-08 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010
7N40	Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex 分子名称: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog 著者 Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. 登録日 2021-06-02 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun, 13, 2022
2YRP	Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4 分子名称: Nuclear factor of activated T-cells, cytoplasmic 4 著者 Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-02 公開日 2008-02-12 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4 To be Published
7NMI	Transactivation domain of p53 in complex with S100P, using annexin A2 as crystallization chaperone 分子名称: CALCIUM ION, Cellular tumor antigen p53, GLYCEROL, ... 著者 Ecsedi, P, Nyitray, L. 登録日 2021-02-23 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Transactivation domain of p53 in complex with S100P using annexin A2 as a crystallization chaperone To Be Published
4XEI	Orthorhombic isomorph of bovine Arp2/3 complex 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Jurgenson, C.J, Pollard, T.P. 登録日 2014-12-23 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.874 Å) 主引用文献 Crystals of the Arp2/3 complex in two new space groups with structural information about actin-related protein 2 and potential WASP binding sites. Acta Crystallogr.,Sect.F, 71, 2015
3ED7	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: SULFATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-09-02 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010

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