3EMH

Structural basis of WDR5-MLL interaction

Summary for 3EMH

Entry DOI	10.2210/pdb3emh/pdb
Descriptor	WD repeat-containing protein 5, Mixed-lineage leukemia protein 1, SULFATE ION, ... (4 entities in total)
Functional Keywords	chromatin, histone, wd40 repeat, nucleus, phosphoprotein, wd repeat, zinc-finger, gene regulation
Biological source	Homo sapiens More
Cellular location	Nucleus: P61964
Total number of polymer chains	2
Total formula weight	36612.42
Authors	Song, J.J.,Kingston, R.E. (deposition date: 2008-09-24, release date: 2008-10-07, Last modification date: 2023-09-06)
Primary citation	Song, J.J.,Kingston, R.E. WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket. J.Biol.Chem., 283:35258-35264, 2008 Cited by PubMed: 18840606 DOI: 10.1074/jbc.M806900200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.37 Å)

Structure validation