3EMH
Structural basis of WDR5-MLL interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 318 | 34916.6 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens | BMP2-induced 3-kb gene protein |
| 2 | B (B) | Mixed-lineage leukemia protein 1 | polymer | 13 | 1503.7 | 1 | UniProt (Q59FF2) UniProt (by SIFTS) (Q03164) | MLL1 | |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 25 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| Pro 22 | - | expression tag |
| Glu 23 | - | expression tag |
| Phe 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36420.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 36612.4 |
