PDB: 242842 件ウェブページステータス検索Chemie searchBIRD

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5A2L	Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MODIFIED ANTIGEN TN, ... 著者 Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. 登録日 2015-05-20 公開日 2015-06-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
7R2T	SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position. 分子名称: CALCIUM ION, GLYCEROL, Synaptojanin-2-binding protein,Annexin, ... 著者 Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. 登録日 2022-02-05 公開日 2023-05-17 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 PDZome-wide and structural characterization of the PDZ-binding motif of VANGL2. Biochim Biophys Acta Proteins Proteom, 1872, 2024
6Z3R	Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Langer, L.M, Gat, Y, Conti, E. 登録日 2020-05-21 公開日 2020-06-24 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. Elife, 9, 2020
7QNT	TarM(Se) native 分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Guo, Y, Stehle, T. 登録日 2021-12-22 公開日 2023-05-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9, 2023
8CPG	Structure of the AT-Hook 1 peptide from the mammalian HMGA protein in complex with DNA 分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*AP*TP*TP*AP*AP*CP*G)-3'), High mobility group protein HMG-I/HMG-Y, MAGNESIUM ION 著者 Boer, D.R, Campos, J.L. 登録日 2023-03-02 公開日 2024-09-11 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the HMGA AT-hook 1 domain bound to the minor groove of AT-rich DNA and inhibition by antikinetoplastid drugs. Sci Rep, 14, 2024
8VTR	Structure of FabS1CE3-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor (orthorhombic form) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... 著者 Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. 登録日 2024-01-26 公開日 2024-07-10 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci., 33, 2024
5UOF	Crystal structure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans 分子名称: 1,2-ETHANEDIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), SERINE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-01-31 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans to be published
8VTP	Structure of FabS1CE-EPR-1, a high affinity antibody for the erythropoeitin receptor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ... 著者 Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sidhu, S.S. 登録日 2024-01-26 公開日 2024-07-10 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci., 33, 2024
6XQP	Structure of human D462-E4 TCR in complex with human MR1-5-OP-RU 分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, BROMIDE ION, Beta-2-microglobulin, ... 著者 Awad, W, Rossjohn, J. 登録日 2020-07-10 公開日 2020-08-26 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Atypical TRAV1-2 - T cell receptor recognition of the antigen-presenting molecule MR1. J.Biol.Chem., 295, 2020
5OB9	X-ray structure of the adduct formed upon reaction of lysozyme with the compound fac-[RuII(CO)3Cl2(N3-MIM), MIM=methyl-imidazole (crystals grown using ethylene glycol 分子名称: 1,2-ETHANEDIOL, Lysozyme C, NITRATE ION, ... 著者 Pontillo, N, Ferraro, G, Merlino, A. 登録日 2017-06-26 公開日 2017-07-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Ru-Based CO releasing molecules with azole ligands: interaction with proteins and the CO release mechanism disclosed by X-ray crystallography. Dalton Trans, 46, 2017
6JOM	Crystal structure of lipoate protein ligase from Mycoplasma hyopneumoniae 分子名称: 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, Lipoate--protein ligase 著者 Zhang, H, Chen, H, Ma, G. 登録日 2019-03-22 公開日 2020-03-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Functional Identification and Structural Analysis of a New Lipoate Protein Ligase inMycoplasma hyopneumoniae. Front Cell Infect Microbiol, 10, 2020
3JST	Crystal structure of transcriptional coactivator/pterin dehydratase from Brucella Melitensis 分子名称: 1,2-ETHANEDIOL, Putative pterin-4-alpha-carbinolamine dehydratase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-10 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of transcriptional coactivator/pterin dehydratase from Brucella Melitensis To be Published
8S1A	c-KIT kinase domain in complex with crenolanib 分子名称: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, Mast/stem cell growth factor receptor Kit 著者 Teuber, A, Mueller, M.P, Rauh, D. 登録日 2024-02-15 公開日 2025-09-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 c-KIT kinase domain in complex with crenolanib To Be Published
1FOA	CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I 分子名称: ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE, GLYCEROL, MANGANESE (II) ION, ... 著者 Unligil, U.M, Zhou, S, Yuwaraj, S, Sarkar, M, Schachter, H, Rini, J.M. 登録日 2000-08-26 公開日 2001-05-16 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily. EMBO J., 19, 2000
8KEC	Cyanophage A-1(L) tail fiber 分子名称: Long tail fiber, short tail fiber 著者 Yu, R.C, Li, Q, Zhou, C.Z. 登録日 2023-08-11 公開日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the intact tail machine of Anabaena myophage A-1(L). Nat Commun, 15, 2024
5LHB	POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017262 分子名称: 1-(cyclopropylmethyl)-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-3-[(2-methyl-1,3-thiazol-5-yl)methyl]quinazoline-2,4-dione, DIMETHYL SULFOXIDE, Poly(ADP-ribose) glycohydrolase, ... 著者 Tucker, J, Barkauskaite, E. 登録日 2016-07-10 公開日 2016-10-12 最終更新日 2025-08-06 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib. ACS Chem. Biol., 11, 2016
8S14	c-KIT kinase domain in complex with sunitinib 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Mast/stem cell growth factor receptor Kit, ... 著者 Teuber, A, Niggenaber, J, Landel, I, Mueller, M.P, Rauh, D. 登録日 2024-02-15 公開日 2025-09-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 c-KIT kinase domain in complex with sunitinib To Be Published
8OFL	Coproporphyrin III - LmCpfC complex soaked 4min with Fe2+ 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Coproporphyrin III ferrochelatase, ... 著者 Gabler, T, Hofbauer, S. 登録日 2023-03-16 公開日 2023-04-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Iron insertion into coproporphyrin III-ferrochelatase complex: Evidence for an intermediate distorted catalytic species. Protein Sci., 32, 2023
6XRM	Crystal structure of human PI3K-gamma in complex with Compound 4 分子名称: 5-[2-amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Walker, N.P, Jeffrey, J.L. 登録日 2020-07-13 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Discovery of Potent and Selective PI3K gamma Inhibitors. J.Med.Chem., 63, 2020
5B0X	Crystal structure of the CK2a/benzoic acid derivative complex 分子名称: 4-[2-[(4-methoxyphenyl)carbonylamino]-1,3-thiazol-5-yl]benzoic acid, Casein kinase II subunit alpha 著者 Kinoshita, T, Nakanishi, I. 登録日 2015-11-13 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors Bioorg.Med.Chem., 24, 2016
6HMX	RIP2 Kinase Catalytic Domain complex with N(4,5dimethyl1Hpyrazol3yl)7methoxy6(2methylpropane2sulfonyl)quinolin4amine 分子名称: 6-~{tert}-butylsulfonyl-~{N}-(3,4-dimethyl-1~{H}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine, Receptor-interacting serine/threonine-protein kinase 2 著者 Convery, M.A, Haile, P.A. 登録日 2018-09-13 公開日 2018-11-07 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett, 9, 2018
1NUV	The Leadzyme Ribozyme Bound to Mg(H2O)6(II) and Sr(II) at 1.8 A resolution 分子名称: 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION, ... 著者 Wedekind, J.E, Mckay, D.B. 登録日 2003-02-01 公開日 2003-08-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation. BIOCHEMISTRY, 42, 2003
5LOT	Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with acetyl-CoA. 分子名称: 3-ketoacyl-CoA thiolase-like protein, ACETYL COENZYME *A 著者 Harijan, R.K, Kiema, T.-R, Wierenga, R.K. 登録日 2016-08-09 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1. Protein Eng. Des. Sel., 30, 2017
6S7B	Crystal structure of CARM1 in complex with inhibitor UM249 分子名称: 1-[4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azanylpropyl)amino]butyl]guanidine, Histone-arginine methyltransferase CARM1 著者 Gunnell, E.A, Muhsen, U, Dowden, J, Dreveny, I. 登録日 2019-07-04 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.659 Å) 主引用文献 Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem.J., 477, 2020
7A5H	Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. 登録日 2020-08-21 公開日 2020-12-23 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020

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