6Z3R

Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ

Summary for 6Z3R

• Entry DOI: 10.2210/pdb6z3r/pdb
• EMDB information: 11063
• Descriptor: Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1, Protein SMG8, Protein SMG9, ... (8 entities in total)
• Functional Keywords: cryo-em, structural biology, nonsense-mediated mrna decay, rna quality control, pikk, nmd, substrate, phosphorylation, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 550062.01

Authors

Langer, L.M.,Gat, Y.,Conti, E. (deposition date: 2020-05-21, release date: 2020-06-24, Last modification date: 2020-10-07)

• Primary citation: Langer, L.M.,Gat, Y.,Bonneau, F.,Conti, E.; Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity.; Elife, 9:-, 2020; PubMed: 32469312; DOI: 10.7554/eLife.57127

Experimental method

ELECTRON MICROSCOPY (2.97 Å)