1NUV

The Leadzyme Ribozyme Bound to Mg(H2O)6(II) and Sr(II) at 1.8 A resolution

Summary for 1NUV

• Entry DOI: 10.2210/pdb1nuv/pdb
• Related: 1LDZ 1NUJ 2LDZ 429D
• Descriptor: 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ribozyme, leadzyme, lead-dependent cleavage, rna, mg(h2o)6(ii), bulged nucleotides, hydrated magnesium, sr(ii), pseudohelical packing, sticky ends, alternate conformation, homopurine base pairs
• Total number of polymer chains: 8
• Total formula weight: 31699.78

Authors

Wedekind, J.E.,Mckay, D.B. (deposition date: 2003-02-01, release date: 2003-08-19, Last modification date: 2024-04-03)

• Primary citation: Wedekind, J.E.,McKay, D.B.; Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation.; BIOCHEMISTRY, 42:9554-9563, 2003; PubMed: 12911297; DOI: 10.1021/bi0300783

Experimental method

X-RAY DIFFRACTION (1.81 Å)