PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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6CEB	Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
3MWE	Truncated Human ATP-Citrate Lyase with Tartrate Bound 分子名称: ATP-citrate synthase, L(+)-TARTARIC ACID, MAGNESIUM ION 著者 Fraser, M.E, Sun, T. 登録日 2010-05-05 公開日 2010-06-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography. J.Biol.Chem., 285, 2010
6CII	Crystal structure of Chlamydomonas reinhardtii THB1 in the cyanomet state 分子名称: CYANIDE ION, Chlamydomonas reinhardtii THB1, PROTOPORPHYRIN IX CONTAINING FE 著者 Martinez, J.E, Schlessman, J.L, Lecomte, J.T.J. 登録日 2018-02-23 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Control of distal lysine coordination in a monomeric hemoglobin: A role for heme peripheral interactions J.Inorg.Biochem., 219, 2021
1EKG	MATURE HUMAN FRATAXIN 分子名称: FRATAXIN 著者 Dhe-Paganon, S, Shigeta, R, Chi, Y.I, Ristow, M, Shoelson, S.E. 登録日 2000-03-08 公開日 2000-11-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human frataxin. J.Biol.Chem., 275, 2000
3QT1	RNA polymerase II variant containing A Chimeric RPB9-C11 subunit 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. 登録日 2011-02-22 公開日 2011-03-23 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Evolution of two modes of intrinsic RNA polymerase transcript cleavage. J.Biol.Chem., 286, 2011
6CRI	Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Morris, K.L, Buffalo, C.Z, Hurley, J.H. 登録日 2018-03-18 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6CTW	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CCL2, beta, gamma dCTP analogue 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 4-amino-1-{2-deoxy-5-O-[(R)-{[(R)-[dichloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-L-threo-pentofuranosyl}pyrimidin-2(1H)-one, CHLORIDE ION, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-23 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CU9	Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-03-24 公開日 2019-03-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE To Be Published
4NXO	Crystal Structure of Insulin Degrading Enzyme in complex with BDM44768 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Liang, W.G, Deprez, R, Deprez, B, Tang, W. 登録日 2013-12-09 公開日 2015-10-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
3GI8	Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment 分子名称: 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609 著者 Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2009-03-05 公開日 2009-08-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structure and mechanism of a na+-independent amino Acid transporter. Science, 325, 2009
2ATI	Glycogen Phosphorylase Inhibitors 分子名称: Glycogen phosphorylase, liver form, N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA, ... 著者 Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.J, Herling, A.W, Oikonomakos, N.G, Schmoll, D, Sarubbi, E, von Roedern, E, Schoenafinger, K, Defossa, E. 登録日 2005-08-25 公開日 2006-08-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. J.Med.Chem., 48, 2005
1EOU	CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN ANTICONVULSANT SUGAR SULFAMATE 分子名称: CARBONIC ANHYDRASE II (CA II), SULFAMIC ACID 2,3-O-(1-METHYLETHYLIDENE)-4,5-O-SULFONYL-BETA-FRUCTOPYRANOSE ESTER, ZINC ION 著者 Recacha, R, Costanzo, M.J, Maryanoff, B.E, Chattopadhyay, D. 登録日 2000-03-24 公開日 2002-02-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate. Biochem.J., 361, 2002
3GDP	Hydroxynitrile lyase from almond, monoclinic crystal form 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Dreveny, I, Gruber, K, Kratky, C. 登録日 2009-02-24 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. Biochemistry, 48, 2009
1ERV	HUMAN THIOREDOXIN MUTANT WITH CYS 73 REPLACED BY SER (REDUCED FORM) 分子名称: THIOREDOXIN 著者 Weichsel, A, Gasdaska, J.R, Powis, G, Montfort, W.R. 登録日 1996-02-07 公開日 1996-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure, 4, 1996
3TR0	Structure of guanylate kinase (gmk) from Coxiella burnetii 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION 著者 Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
6CR5	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH2-beta, gamma dATP analogue 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl]adenosine, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
3U4C	Crystal structure of YwfH, NADPH dependent reductase involved in Bacilysin biosynthesis 分子名称: Bacilysin biosynthesis oxidoreductase ywfH, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Rajavel, M, Gopal, B. 登録日 2011-10-07 公開日 2013-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural insights into the role of Bacillus subtilis YwfH (BacG) in tetrahydrotyrosine synthesis Acta Crystallogr.,Sect.D, 69, 2013
3PSC	Bovine GRK2 in complex with Gbetagamma subunits 分子名称: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 著者 Thal, D.M, Tesmer, J.J. 登録日 2010-12-01 公開日 2011-06-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors. Mol.Pharmacol., 80, 2011
5BK9	AAD-1 Bound to the Vanadyl Ion and Succinate 分子名称: (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, PHOSPHATE ION, SUCCINIC ACID, ... 著者 Ongpipattanakul, C, Chekan, J.R. 登録日 2019-06-01 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
3PFQ	Crystal Structure and Allosteric Activation of Protein Kinase C beta II 分子名称: CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase C beta type, ... 著者 Leonard, T.A, Rozycki, B, Saidi, L.F, Hummer, G, Hurley, J.H. 登録日 2010-10-28 公開日 2011-02-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Crystal Structure and Allosteric Activation of Protein Kinase C beta II Cell(Cambridge,Mass.), 144, 2011
6CRH	Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-03-17 公開日 2019-03-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.327 Å) 主引用文献 Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion. Molecules, 24, 2019
3PF7	Crystal structure of BoxB with malonate bound to the diiron center 分子名称: Benzoyl-CoA oxygenase component B, CHLORIDE ION, FE (III) ION, ... 著者 Weinert, T, Rather, L.J, Fuchs, G, Ermler, U. 登録日 2010-10-28 公開日 2011-06-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB. J.Biol.Chem., 286, 2011
6D3R	Thermostablilized dephosphorylated chicken CFTR 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator 著者 Fay, J.F, Riordan, J.R. 登録日 2018-04-16 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. Biochemistry, 57, 2018
4J7A	Crystal Structure of Est25 - a Bacterial Homolog of Hormone-Sensitive Lipase from a Metagenomic Library 分子名称: Esterase 著者 Ngo, T.D, Ryu, B.H, Ju, H.S, Jang, E.J, Park, K.S, Joo, S.B, Kim, K.K, Kim, D.H. 登録日 2013-02-13 公開日 2014-01-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.492 Å) 主引用文献 Structural and functional analyses of a bacterial homologue of hormone-sensitive lipase from a metagenomic library Acta Crystallogr.,Sect.D, 69, 2014
3E1P	Crystal structure of E. coli Bacterioferritin (BFR) in which the Ferroxidase centre is inhibited with ZN(II) and high occupancy iron is bound within the cavity. 分子名称: BACTERIOFERRITIN, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Crow, A, Lawson, T, Lewin, A, Moore, G.R, Le Brun, N. 登録日 2008-08-04 公開日 2009-05-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for iron mineralization by bacterioferritin J.Am.Chem.Soc., 131, 2009

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