1EOU

CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN ANTICONVULSANT SUGAR SULFAMATE

Summary for 1EOU

• Entry DOI: 10.2210/pdb1eou/pdb
• Related: 1AM6
• Descriptor: CARBONIC ANHYDRASE II (CA II), ZINC ION, SULFAMIC ACID 2,3-O-(1-METHYLETHYLIDENE)-4,5-O-SULFONYL-BETA-FRUCTOPYRANOSE ESTER, ... (4 entities in total)
• Functional Keywords: hydrolase, co2 hydration, protein-inhibitor complex, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29715.82

Authors

Recacha, R.,Costanzo, M.J.,Maryanoff, B.E.,Chattopadhyay, D. (deposition date: 2000-03-24, release date: 2002-02-13, Last modification date: 2024-03-13)

• Primary citation: Recacha, R.,Costanzo, M.J.,Maryanoff, B.E.,Chattopadhyay, D.; Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate.; Biochem.J., 361:437-441, 2002; PubMed: 11802772; DOI: 10.1042/0264-6021:3610437

Experimental method

X-RAY DIFFRACTION (2.1 Å)