PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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4MOG	Pyranose 2-oxidase V546C mutant with 3-fluorinated glucose 分子名称: 3-deoxy-3-fluoro-beta-D-glucopyranose, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase 著者 Tan, T.C, Spadiut, O, Gandini, R, Haltrich, D, Divne, C. 登録日 2013-09-12 公開日 2014-02-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Binding of Fluorinated Glucose and Galactose to Trametes multicolor Pyranose 2-Oxidase Variants with Improved Galactose Conversion. Plos One, 9, 2014
4MQ2	The crystal structure of DYRK1a with a bound pyrido[2,3-d]pyrimidine inhibitor 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, PENTAETHYLENE GLYCOL, SULFATE ION, ... 著者 Lukacs, C.M, Janson, C.A, Garvie, C, Liang, L. 登録日 2013-09-15 公開日 2013-12-11 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
6MCK	p97 D1D2 with CB5083 bound 分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2018-08-31 公開日 2019-01-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.77 Å) 主引用文献 Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083. Mol. Pharmacol., 95, 2019
1X92	CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D-MANNOPYRANOSE-7-PHOSPHATE 分子名称: 7-O-phosphono-D-glycero-alpha-D-manno-heptopyranose, PHOSPHOHEPTOSE ISOMERASE 著者 Walker, J.R, Evdokimova, E, Kudritska, M, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) 登録日 2004-08-19 公開日 2004-10-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. J.Biol.Chem., 283, 2008
1S19	Crystal structure of VDR ligand binding domain complexed to calcipotriol. 分子名称: CALCIPOTRIOL, Vitamin D3 receptor 著者 Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. 登録日 2004-01-06 公開日 2004-04-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J.Med.Chem., 47, 2004
4K0X	X-ray Crystal Structure of OXA-23 from Acinetobacter baumannii 分子名称: BICARBONATE ION, Beta-lactamase 著者 Klinger, N.V, Ramey, M.E, Leonard, D.A, Powers, R.A. 登録日 2013-04-04 公開日 2013-08-07 最終更新日 2013-10-23 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam. Antimicrob.Agents Chemother., 57, 2013
4NAO	Crystal structure of EasH 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, HEXAETHYLENE GLYCOL, ... 著者 Janke, R, Havemann, J, Vogel, D, Keller, U, Loll, B. 登録日 2013-10-22 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.649 Å) 主引用文献 Cyclolization of d-lysergic Acid alkaloid peptides. Chem.Biol., 21, 2014
6MP8	X-ray crystal structure of VioC bound to Fe(II), D-arginine, and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent L-arginine hydroxylase, D-ARGININE, ... 著者 Dunham, N.P, Boal, A.K. 登録日 2018-10-05 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 alpha-Amine Desaturation of d-Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l-Arginine 3-Hydroxylase, VioC. Biochemistry, 57, 2018
1IV1	Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 著者 Kishida, H, Wada, T, Unzai, S, Kuzuyama, T, Terada, T, Sirouzu, M, Yokoyama, S, Tame, J.R.H, Park, S.-Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-03-11 公開日 2002-09-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis. Acta Crystallogr.,Sect.D, 59, 2003
2DU0	Crystal structure of basic winged bean lectin in complex with Alpha-D-galactose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Basic agglutinin, CALCIUM ION, ... 著者 Kulkarni, K.A, Katiyar, S, Surolia, A, Vijayan, M, Suguna, K. 登録日 2006-07-19 公開日 2006-11-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc ACTA CRYSTALLOGR.,SECT.D, 62, 2006
1S1O	NMR Structure of a D,L Alternating pentadecamer of norleucine: double antiparallel beta-helix 分子名称: BOC-L-NLE-(D-NLE-L-NLE)5-D-NLE(METHYL)-L-NLE-D-NLE-L-NLE METHYL ESTER 著者 Navarro, E, Fennude, E, Celda, B. 登録日 2004-01-07 公開日 2004-02-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of a D,L-alternating oligonorleucine as a model of double-stranded antiparallel beta-helix. Biopolymers, 64, 2002
1JCT	Glucarate Dehydratase, N341L mutant Orthorhombic Form 分子名称: D-GLUCARATE, Glucarate Dehydratase, ISOPROPYL ALCOHOL, ... 著者 Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. 登録日 2001-06-11 公開日 2001-09-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry, 40, 2001
4G31	Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution 分子名称: 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL 著者 Gampe, R.T, Axten, J.M. 登録日 2012-07-13 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
1AE8	HUMAN ALPHA-THROMBIN INHIBITION BY EOC-D-PHE-PRO-AZALYS-ONP 分子名称: 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ... 著者 De Simone, G, Balliano, G, Milla, P, Gallina, C, Giordano, C, Tarricone, C, Rizzi, M, Bolognesi, M, Ascenzi, P. 登録日 1997-03-06 公開日 1997-12-03 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. J.Mol.Biol., 269, 1997
1NFG	Structure of D-hydantoinase 分子名称: D-hydantoinase, ZINC ION 著者 Xu, Z, Yang, Y, Jiang, W, Arnold, E, Ding, J. 登録日 2002-12-14 公開日 2003-07-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of D-Hydantoinase from Burkholderia pickettii at a Resolution of 2.7 Angstroms: Insights into the Molecular Basis of Enzyme Thermostability. J.Bacteriol., 185, 2003
2OVW	ENDOGLUCANASE I COMPLEXED WITH CELLOBIOSE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Sulzenbacher, G, Davies, G.J, Schulein, M. 登録日 1997-04-04 公開日 1998-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the endoglucanase I from Fusarium oxysporum: native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 A resolution. Biochemistry, 36, 1997
2DTY	Crystal structure of basic winged bean lectin complexed with N-acetyl-D-galactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Basic agglutinin, CALCIUM ION, ... 著者 Kulkarni, K.A, Katiyar, S, Surolia, A, Vijayan, M, Suguna, K. 登録日 2006-07-19 公開日 2006-11-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc ACTA CRYSTALLOGR.,SECT.D, 62, 2006
3QHD	Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to CYTIDINE, FOL795 and FOL955 分子名称: 2-(pyridin-3-yl)-1,3-thiazole-4-carbaldehyde, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-(1H-IMIDAZOL-1-YL)PHENOL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-01-25 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
1SO0	Crystal structure of human galactose mutarotase complexed with galactose 分子名称: aldose 1-epimerase, beta-D-galactopyranose 著者 Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2004-03-12 公開日 2004-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular structure of human galactose mutarotase J.Biol.Chem., 279, 2004
2YRS	Human hemoglobin D Los Angeles: crystal structure 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Poy, C.D, Moreno, F, Bonini-Domingos, C.R, Filgueira de Azevedo Jr, W, Bonilla-Rodriguez, G.O. 登録日 2007-04-03 公開日 2008-03-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Human Hemoglobin D Los Angeles: crystal structure to be published
4LX5	X-ray crystal structure of the M6" riboswitch aptamer bound to pyrimido[4,5-d]pyrimidine-2,4-diamine (PPDA) 分子名称: MAGNESIUM ION, Mutated adenine riboswitch aptamer, pyrimido[4,5-d]pyrimidine-2,4-diamine 著者 Dunstan, M.S, Leys, D. 登録日 2013-07-29 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Modular riboswitch toolsets for synthetic genetic control in diverse bacterial species. J.Am.Chem.Soc., 136, 2014
3EHB	A D-Pathway Mutation Decouples the Paracoccus Denitrificans Cytochrome c Oxidase by Altering the side chain orientation of a distant, conserved Glutamate 分子名称: CALCIUM ION, COPPER (II) ION, Cytochrome c oxidase subunit 1-beta, ... 著者 Koepke, J, Mueller, H, Peng, G. 登録日 2008-09-12 公開日 2008-09-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 A d-pathway mutation decouples the paracoccusdenitrificans cytochrome C oxidase by altering the side-chain orientation of a distant conserved glutamate J.Mol.Biol., 384, 2008
3EKU	Crystal Structure of Monomeric Actin bound to Cytochalasin D 分子名称: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... 著者 Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. 登録日 2008-09-19 公開日 2008-10-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of monomeric actin bound to cytochalasin D. J.Mol.Biol., 384, 2008
1PE1	Aquifex aeolicus KDO8PS in complex with cadmium and 2-PGA 分子名称: 2-PHOSPHOGLYCERIC ACID, 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, ... 著者 Wang, J, Xu, X, Grison, C, Petek, S, Coutrot, P, Birck, M.R, Woodard, R.W, Gatti, D.L. 登録日 2003-05-20 公開日 2004-02-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase DRUG DES.DISCOVERY, 18, 2003
1TAN	TANDEM DNA, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(P*CP*AP*GP*C)-3'), DNA (5'-D(P*TP*CP*CP*A)-3'), DNA (5'-D(P*TP*GP*GP*AP*GP*CP*TP*G)-3') 著者 Denisov, A, Sandstrom, A, Maltseva, T, Pyshnyi, D, Ivanova, E, Zarytova, V, Chattopadhyaya, J. 登録日 1997-06-17 公開日 1997-09-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The NMR structure of estrone (Es)-tethered tandem DNA duplex: [d(5'pCAGCp3')-Es] + [Es-d(5'pTCCA3')]: d(5'pTGGAGCTG3'). J.Biomol.Struct.Dyn., 15, 1997

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