1X92

CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D-MANNOPYRANOSE-7-PHOSPHATE

Summary for 1X92

Entry DOI	10.2210/pdb1x92/pdb
Descriptor	PHOSPHOHEPTOSE ISOMERASE, 7-O-phosphono-D-glycero-alpha-D-manno-heptopyranose (3 entities in total)
Functional Keywords	midwest centre for structural genomics, sis domain, a/b protein, lipopolysaccharide biosynthesis, psi, protein structure initiative, midwest center for structural genomics, mcsg, isomerase
Biological source	Pseudomonas aeruginosa
Cellular location	Cytoplasm (By similarity): Q9HVZ0
Total number of polymer chains	2
Total formula weight	43837.32
Authors	Walker, J.R.,Evdokimova, E.,Kudritska, M.,Joachimiak, A.,Edwards, A.,Savchenko, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2004-08-19, release date: 2004-10-26, Last modification date: 2024-04-03)
Primary citation	Taylor, P.L.,Blakely, K.M.,de Leon, G.P.,Walker, J.R.,McArthur, F.,Evdokimova, E.,Zhang, K.,Valvano, M.A.,Wright, G.D.,Junop, M.S. Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. J.Biol.Chem., 283:2835-2845, 2008 Cited by PubMed: 18056714 DOI: 10.1074/jbc.M706163200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation