PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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3TO8	Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L) 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Heterogeneous nuclear ribonucleoprotein L, ... 著者 Zhang, W.J, Zeng, F.X, Liu, Y.W, Zhao, Y, Niu, L.W, Teng, M.K, Li, X. 登録日 2011-09-04 公開日 2012-03-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L) To be Published
3TU9	Crystal structure of rabbit muscle aldolase bound with 5-O-methyl mannitol 1,6-phosphate 分子名称: 2-O-methyl-1,6-di-O-phosphono-D-mannitol, Fructose-bisphosphate aldolase A 著者 Arthus-Cartier, G, Sygusch, J. 登録日 2011-09-16 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases. ACS Med Chem Lett, 2, 2011
2QQS	JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide 分子名称: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE 著者 Lee, J, Botuyan, M.V, Mer, G. 登録日 2007-07-26 公開日 2007-12-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15, 2008
2QUT	Dihydroxyacetone phosphate enamine intermediate in fructose-1,6-bisphosphate aldolase from rabbit muscle 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase A 著者 St-Jean, M, Sygusch, J. 登録日 2007-08-06 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase J.Biol.Chem., 282, 2007
2R6M	Crystal structure of rat CK2-beta subunit 分子名称: Casein kinase II subunit beta, ZINC ION 著者 Shen, Y. 登録日 2007-09-06 公開日 2008-09-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2 CHIN.SCI.BULL., 54, 2009
4KM9	Crystal structure of human Suppressor of Fused 分子名称: Suppressor of fused homolog 著者 Zhang, Y, Qi, X, Zhang, Z, Wu, G. 登録日 2013-05-08 公開日 2013-11-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun, 4, 2013
2RRD	Structure of HRDC domain from human Bloom syndrome protein, BLM 分子名称: HRDC domain from Bloom syndrome protein 著者 Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K. 登録日 2010-07-19 公開日 2010-09-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the HRDC domain of human Bloom syndrome protein BLM J.Biochem., 148, 2010
2TSR	THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX 著者 Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. 登録日 1998-06-19 公開日 1999-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
2RD6	PARP complexed with A861695 分子名称: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1 著者 Park, C.H. 登録日 2007-09-21 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 PARP complexed with A861695 To be Published
2RVM	Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail 分子名称: Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
4KXX	Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate 分子名称: (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ... 著者 Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
2RS8	Solution structure of the N-terminal RNA recognition motif of NonO 分子名称: Non-POU domain-containing octamer-binding protein 著者 Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-11-29 公開日 2012-12-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal RNA recognition motif of NonO To be Published
2RRA	Solution structure of RNA binding domain in human Tra2 beta protein in complex with RNA (GAAGAA) 分子名称: 5'-R(*GP*AP*AP*GP*AP*A)-3', cDNA FLJ40872 fis, clone TUTER2000283, ... 著者 Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Sugano, S, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2010-06-17 公開日 2011-04-27 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for the dual RNA-recognition modes of human Tra2-beta RRM. Nucleic Acids Res., 39, 2011
4KXU	Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate 分子名称: 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ... 著者 Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
2RDA	Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195 分子名称: BETA-MERCAPTOETHANOL, PHOSPHATE ION, Thymidylate synthase 著者 Gibson, L.M, Lovelace, L.L, Lebioda, L. 登録日 2007-09-21 公開日 2008-06-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195. Biochemistry, 47, 2008
4LY1	Structure of Human HDAC2 in complex with inhibitor 4-(acetylamino)-N-[2-amino-5-(thiophen-2-yl)phenyl]benzamide 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-(acetylamino)-N-[2-amino-5-(thiophen-2-yl)phenyl]benzamide, CALCIUM ION, ... 著者 Fong, R, Lupardus, P.J. 登録日 2013-07-30 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability. J.Biol.Chem., 288, 2013
2RR9	The solution structure of the K63-Ub2:tUIMs complex 分子名称: Putative uncharacterized protein UIMC1, ubiquitin 著者 Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M. 登録日 2010-06-16 公開日 2011-07-06 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 The solution structure of the K63-Ub2:tUIMs complex To be Published
2RIQ	Crystal Structure of the Third Zinc-binding domain of human PARP-1 分子名称: ETHANOL, GLYCEROL, Poly [ADP-ribose] polymerase 1, ... 著者 Pascal, J.M, Langelier, M.F, Servent, K.M. 登録日 2007-10-12 公開日 2008-01-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Third Zinc-binding Domain of Human Poly(ADP-ribose) Polymerase-1 Coordinates DNA-dependent Enzyme Activation. J.Biol.Chem., 283, 2008
2RMA	Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A 分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 著者 Ke, H, Mayrose, D. 登録日 1994-01-07 公開日 1995-02-07 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Cyclophilin a Complexed with Cyclosporin a and N-Methyl-4-[(E)-2-Butenyl]-4,4-Dimethylthreonine Cyclosporin A. Structure, 2, 1994
2RMS	Solution structure of the mSin3A PAH1-SAP25 SID complex 分子名称: MSin3A-binding protein, Paired amphipathic helix protein Sin3a 著者 Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. 登録日 2007-11-14 公開日 2008-01-22 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor J.Mol.Biol., 375, 2007
4MD8	Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E) 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
4LR6	Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment 分子名称: 3-methyl-4-phenyl-1,2-oxazol-5-amine, Bromodomain-containing protein 4, FORMIC ACID 著者 Jayaram, H, Poy, F, Gehling, V, Hewitt, M, Vaswani, R, Leblanc, Y, Cote, A, Nasveschuk, C, Taylor, A, Harmange, J.-C, Audia, J, Pardo, E, Joshi, S, Sandy, P, Mertz, J, Sims, R, Bergeron, L, Bryant, B, Ravichandran, S, Yellapuntala, S, Nandana, B.S, Birudukota, S, Albrecht, B, Bellon, S. 登録日 2013-07-19 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. ACS Med Chem Lett, 4, 2013
2RNY	Complex Structures of CBP Bromodomain with H4 ack20 Peptide 分子名称: CREB-binding protein, Histone H4 著者 Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. 登録日 2008-02-03 公開日 2008-05-06 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Structure, 16, 2008
2RPC	Solution structure of the tandem zf-C2H2 domains from the human zinc finger protein ZIC 3 分子名称: ZINC ION, Zinc finger protein ZIC 3 著者 Tomizawa, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-05-14 公開日 2009-03-31 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain Hum.Mol.Genet., 17, 2008
4LRG	Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide 分子名称: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide, Bromodomain-containing protein 4 著者 Ravichandran, S, Jayaram, H, Poy, F, Gehling, V, Hewitt, M, Vaswani, R, Leblanc, Y, Cote, A, Nasveschuk, C, Taylor, A, Harmange, J.-C, Audia, J, Pardo, E, Joshi, S, Sandy, P, Mertz, J, Sims, R, Bergeron, L, Bryant, B, Yellapuntala, S, Nandana, B.S, Birudukota, S, Albrecht, B, Bellon, S. 登録日 2013-07-19 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. ACS Med Chem Lett, 4, 2013

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