2QQS

JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide

Summary for 2QQS

Entry DOI	10.2210/pdb2qqs/pdb
Related	2QQR
Descriptor	JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE (3 entities in total)
Functional Keywords	histone lysine demethylase, metal binding protein, protein-methylated peptide complex, chromatin regulator, dioxygenase, host-virus interaction, iron, metal-binding, nucleus, oxidoreductase, phosphorylation, polymorphism, transcription, transcription regulation, zinc, zinc-finger
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: O75164
Total number of polymer chains	4
Total formula weight	29650.96
Authors	Lee, J.,Botuyan, M.V.,Mer, G. (deposition date: 2007-07-26, release date: 2007-12-11, Last modification date: 2023-08-30)
Primary citation	Lee, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15:109-111, 2008 Cited by PubMed: 18084306 DOI: 10.1038/nsmb1326 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation