2RPC

Solution structure of the tandem zf-C2H2 domains from the human zinc finger protein ZIC 3

Summary for 2RPC

Entry DOI	10.2210/pdb2rpc/pdb
Descriptor	Zinc finger protein ZIC 3, ZINC ION (2 entities in total)
Functional Keywords	zf-c2h2, zinc finger protein of the cerebellum 3, zic3, disease mutation, dna-binding, metal-binding, nucleus, polymorphism, transcription, transcription regulation, zinc, zinc-finger, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
Biological source	Homo sapiens (Human)
Cellular location	Nucleus: O60481
Total number of polymer chains	1
Total formula weight	17866.62
Authors	Tomizawa, T.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-05-14, release date: 2009-03-31, Last modification date: 2022-03-16)
Primary citation	Hatayama, M.,Tomizawa, T.,Sakai-Kato, K.,Bouvagnet, P.,Kose, S.,Imamoto, N.,Yokoyama, S.,Utsunomiya-Tate, N.,Mikoshiba, K.,Kigawa, T.,Aruga, J. Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain Hum.Mol.Genet., 17:3459-3473, 2008 Cited by PubMed: 18716025 DOI: 10.1093/hmg/ddn239 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation