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5DG9
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BU of 5dg9 by Molmil
CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dGMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, Egli, M.
登録日2015-08-27
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
4NXZ
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DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site
分子名称: 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-12-09
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.557 Å)
主引用文献Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
2X8R
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BU of 2x8r by Molmil
The structure of a family GH25 lysozyme from Aspergillus fumigatus
分子名称: CHLORIDE ION, GLYCOSYL HYDROLASE
著者Korczynska, J.E, Danielsen, S, Schagerlof, U, Turkenburg, J.P, Davies, G.J, Wilson, K.S, Taylor, E.J.
登録日2010-03-11
公開日2010-09-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of a Family Gh25 Lysozyme from Aspergillus Fumigatus
Acta Crystallogr.,Sect.F, 66, 2010
4NY8
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DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-12-10
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
2WWR
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BU of 2wwr by Molmil
Crystal Structure of Human Glyoxylate Reductase Hydroxypyruvate Reductase
分子名称: GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE, MAGNESIUM ION
著者Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L.
登録日2009-10-26
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase.
J.Mol.Biol., 360, 2006
5DGF
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BU of 5dgf by Molmil
Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-27
公開日2016-12-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
3DGZ
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BU of 3dgz by Molmil
Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 2, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Eckenroth, B.E, Hondal, R.J, Everse, S.J.
登録日2008-06-16
公開日2009-06-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation
To be Published
3DKQ
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BU of 3dkq by Molmil
Crystal structure of Putative Oxygenase (YP_001051978.1) from SHEWANELLA BALTICA OS155 at 2.26 A resolution
分子名称: GLYCEROL, IMIDAZOLE, NICKEL (II) ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-06-25
公開日2008-08-12
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of Putative Oxygenase (YP_001051978.1) from SHEWANELLA BALTICA OS155 at 2.26 A resolution
To be published
6NO7
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BU of 6no7 by Molmil
Crystal Structure of the full-length wild-type PKA RIa Holoenzyme
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Lu, T, Wu, J, Taylor, S.S.
登録日2019-01-15
公開日2019-07-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Two PKA RI alpha holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP.
Proc.Natl.Acad.Sci.USA, 116, 2019
2FUU
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BU of 2fuu by Molmil
NMR solution structure of the PHD domain from the human BPTF in complex with H3(1-15)K4me3 peptide
分子名称: Histone H3, ZINC ION, bromodomain PHD finger transcription factor
著者Ilin, S, Patel, D.J.
登録日2006-01-27
公開日2006-07-11
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3DJG
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BU of 3djg by Molmil
Catalytic cycle of human glutathione reductase near 1 A resolution
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Berkholz, D.S, Faber, H.R, Savvides, S.N, Karplus, P.A.
登録日2008-06-23
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Catalytic cycle of human glutathione reductase near 1 A resolution.
J.Mol.Biol., 382, 2008
6NQ1
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BU of 6nq1 by Molmil
Cryo-EM structure of human TPC2 channel in the apo state
分子名称: Two pore calcium channel protein 2
著者She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y.
登録日2019-01-18
公開日2019-03-27
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural mechanisms of phospholipid activation of the human TPC2 channel.
Elife, 8, 2019
2X75
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BU of 2x75 by Molmil
Staphylococcus aureus adenylosuccinate lyase
分子名称: ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, CHLORIDE ION, ...
著者Fyfe, P.K, Dawson, A, Hutchison, M.T, Cameron, S, Hunter, W.N.
登録日2010-02-23
公開日2010-03-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Staphylococcus Aureus Adenylosuccinate Lyase (Purb) and Assessment of its Potential as a Target for Structure-Based Inhibitor Discovery.
Acta Crystallogr.,Sect.D, 66, 2010
6AU6
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BU of 6au6 by Molmil
Crystal structure of GDP-bound human GNAS R201C mutant
分子名称: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Hu, Q, Shokat, K.M.
登録日2017-08-30
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Disease-Causing Mutations in the G Protein G alpha s Subvert the Roles of GDP and GTP.
Cell, 173, 2018
3BZC
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BU of 3bzc by Molmil
Crystal Structure of the Tex protein from Pseudomonas aeruginosa, crystal form I
分子名称: Tex
著者Johnson, S.J, Close, D, Hill, C.P.
登録日2008-01-17
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa.
J.Mol.Biol., 377, 2008
4B7W
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BU of 4b7w by Molmil
Ligand binding domain human hepatocyte nuclear factor 4alpha: Apo form
分子名称: HEPATOCYTE NUCLEAR FACTOR 4-ALPHA
著者Dudasova, Z, Okvist, M, Kretova, M, Ondrovicova, G, Skrabana, R, LeGuevel, R, Salbert, G, Leonard, G, McSweeney, S, Barath, P.
登録日2012-08-24
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Fatty Acids are not Essential Structural Components of Hepatocyte Nuclear Factor 4Alpha
To be Published
5B72
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BU of 5b72 by Molmil
Crystal structure of bovine lactoperoxidase with a broken covalent bond between Glu258 and heme moiety at 1.98 A resolution.
分子名称: 1-(OXIDOSULFANYL)METHANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Singh, P.K, Sirohi, H.V, Kaur, P, Sharma, S, Singh, T.P.
登録日2016-06-03
公開日2016-07-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of bovine lactoperoxidase with a partially linked heme moiety at 1.98 angstrom resolution
Biochim. Biophys. Acta, 1865, 2016
3DGH
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BU of 3dgh by Molmil
Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thioredoxin reductase 1, ...
著者Eckenroth, B.E, Hondal, R.J, Everse, S.J.
登録日2008-06-13
公開日2009-06-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.745 Å)
主引用文献Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation
To be Published
6CR4
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BU of 6cr4 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
著者Batra, V.K, Wilson, S.H.
登録日2018-03-16
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
4JCQ
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BU of 4jcq by Molmil
ClpP1 from Listeria monocytogenes
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Zeiler, E, List, A, Alte, F, Gersch, M, Wachtel, R, Groll, M, Sieber, S.
登録日2013-02-22
公開日2013-06-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad.
Proc.Natl.Acad.Sci.USA, 110, 2013
6D3S
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BU of 6d3s by Molmil
Thermostabilized phosphorylated chicken CFTR
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator
著者Fay, J.F, Riordan, J.R, Chen, Z.J.
登録日2018-04-16
公開日2018-10-17
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel.
Biochemistry, 57, 2018
6NKR
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BU of 6nkr by Molmil
Ternary complex crystal structure of K289M variant of DNA polymerase Beta with dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2019-01-07
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Biochemistry, 59, 2020
3DJD
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BU of 3djd by Molmil
Crystal structure of the deglycating enzyme fructosamine oxidase from Aspergillus fumigatus (Amadoriase II)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine: oxygen oxidoreductase
著者Collard, F, Zhang, J, Nemet, I, Qanungo, K.R, Monnier, V.M, Yee, V.C.
登録日2008-06-23
公開日2008-07-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the deglycating enzyme fructosamine oxidase (FAOX-II)
To be Published
3DKT
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Crystal structure of Thermotoga maritima encapsulin
分子名称: Maritimacin, Putative uncharacterized protein
著者Sutter, M, Boehringer, D, Gutmann, S, Weber-Ban, E, Ban, N.
登録日2008-06-26
公開日2008-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structural basis of enzyme encapsulation into a bacterial nanocompartment
Nat.Struct.Mol.Biol., 15, 2008
6NKU
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BU of 6nku by Molmil
Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2019-01-07
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Biochemistry, 59, 2020

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