6AU6
Crystal structure of GDP-bound human GNAS R201C mutant
Summary for 6AU6
| Entry DOI | 10.2210/pdb6au6/pdb |
| Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | g protein, gdp, active conformation, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 44707.91 |
| Authors | Hu, Q.,Shokat, K.M. (deposition date: 2017-08-30, release date: 2018-05-09, Last modification date: 2023-10-04) |
| Primary citation | Hu, Q.,Shokat, K.M. Disease-Causing Mutations in the G Protein G alpha s Subvert the Roles of GDP and GTP. Cell, 173:1254-1264.e11, 2018 Cited by PubMed: 29628140DOI: 10.1016/j.cell.2018.03.018 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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