PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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3ZKS	BACE2 XAPERONE COMPLEX WITH INHIBITOR 分子名称: 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide, BETA-SECRETASE 2, XA4813 著者 Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. 登録日 2013-01-24 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
3G9C	Crystal structure of the product Bacillus anthracis glmS ribozyme 分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GLMS RIBOZYME, MAGNESIUM ION, ... 著者 Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. 登録日 2009-02-13 公開日 2009-11-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme Biochemistry, 48, 2009
3TGY	Crystal structure of the complex of Bovine Lactoperoxidase with Ascorbic acid at 2.35 A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yamini, S, Singh, R.P, Singh, A.K, Pandey, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2011-08-18 公開日 2011-09-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of bovine lactoperoxidase with a partially linked heme moiety at 1.98 angstrom resolution. Biochim.Biophys.Acta, 1865, 2017
6NQ8	Crystal structure of YetJ mutant from Bacillus Subtilis - D171E 分子名称: Uncharacterized protein YetJ 著者 Guo, G, Chang, Y, Liu, Q. 登録日 2019-01-19 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Ion and pH Sensitivity of a TMBIM Ca2+Channel. Structure, 27, 2019
6NBH	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
4HX4	Structure of MNTR mutant E11K complexed with Mn2+ 分子名称: MANGANESE (II) ION, TRANSCRIPTIONAL REGULATOR MNTR 著者 Glasfeld, A, McGuire, A. 登録日 2012-11-09 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Roles of the A and C Sites in the Manganese-Specific Activation of MntR. Biochemistry, 52, 2013
6AUM	Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid. 分子名称: 4-{[trans-4-({[4-(trifluoromethoxy)phenyl]carbamoyl}amino)cyclohexyl]oxy}benzoic acid, Bifunctional epoxide hydrolase 2, CHLORIDE ION, ... 著者 Kodani, S.D, Bahkta, S, Hwang, S.H, Pakhomova, S, Newcomer, M.E, Morisseau, C, Hammock, B. 登録日 2017-09-01 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg. Med. Chem. Lett., 28, 2018
3GDN	Almond hydroxynitrile lyase in complex with benzaldehyde 分子名称: (2R)-hydroxy(phenyl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Dreveny, I, Gruber, K, Kratky, C. 登録日 2009-02-24 公開日 2009-03-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. Biochemistry, 48, 2009
4HZI	Crystal structure of the Leptospira interrogans ATPase subunit of an orphan ABC transporter 分子名称: ABC transporter ATP-binding protein, SULFATE ION 著者 Saul, F.A, Haouz, A, Picardeau, M. 登録日 2012-11-15 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Functional Characterization of an Orphan ATP-Binding Cassette ATPase Involved in Manganese Utilization and Tolerance in Leptospira spp. J.Bacteriol., 195, 2013
3P44	Human carbonic anhydrase II in complex with p-(4-ruthenocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-06 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
5D4C	Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
2FFK	Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta, minimized average structure 分子名称: Small inducible cytokine A4, rabbitpox encoded CC chemokine inhibitor 著者 Zhang, L. 登録日 2005-12-19 公開日 2006-08-22 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta. Proc.Natl.Acad.Sci.Usa, 103, 2006
3OYS	Human Carbonic Anhydrase II complexed with 2-{[4-AMINO-3-(3-HYDROXYPROP-1-YN-1-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]METHYL}-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE 分子名称: 2-phenyl-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Aggarwal, M, McKenna, R. 登録日 2010-09-23 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.538 Å) 主引用文献 Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. J.Med.Chem., 54, 2011
3OZJ	Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1 分子名称: (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate, Retinoic acid receptor RXR-alpha, SRC-1, ... 著者 Zhang, H, Li, L, Chen, L, Hu, L, Shen, X. 登録日 2010-09-25 公開日 2011-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode J.Mol.Biol., 407, 2011
2X0G	X-RAY STRUCTURE OF A DAP-KINASE CALMODULIN COMPLEX 分子名称: CALCIUM ION, CALMODULIN, DEATH-ASSOCIATED PROTEIN KINASE 1, ... 著者 Kuper, J, De Diego, I, Lehmann, F, Wilmanns, M. 登録日 2009-12-08 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Basis of the Death-Associated Protein Kinase-Calcium/Calmodulin Regulator Complex. Sci.Signal, 3, 2010
4JIR	Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... 著者 Zhang, L, Zheng, X, Zhang, H, Zhao, Y, Chen, K, Zhai, J, Hu, X. 登録日 2013-03-06 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111). Febs Lett., 587, 2013
3P6C	Human adipocyte lipid-binding protein FABP4 in complex with citric acid 分子名称: CITRIC ACID, Fatty acid-binding protein, adipocyte 著者 Gonzalez, J.M, Pozharski, E. 登録日 2010-10-11 公開日 2011-04-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4). Acta Crystallogr F Struct Biol Commun, 71, 2015
3GI9	Crystal Structure of ApcT Transporter Bound to 7F11 Monoclonal Fab Fragment 分子名称: 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609 著者 Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2009-03-05 公開日 2009-08-18 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Structure and mechanism of a na+-independent amino Acid transporter. Science, 325, 2009
3P0M	Human cAMP-dependent protein kinase in complex with an inhibitor 分子名称: (2R)-4-amino-N'-[(1E)-(3-bromo-4-hydroxyphenyl)methylidene]-2-phenylbutanehydrazide, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Koester, H, Heine, A, Klebe, G. 登録日 2010-09-29 公開日 2011-09-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Fragment based drug design on PKA To be Published
2X3J	CO-COMPLEX STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D (ACSD) WITH ATP AND N-CITRYL-ETHYLENEDIAMINE FROM PECTOBACTERIUM CHRYSANTHEMI 分子名称: (2S)-2-{2-[(2-AMINOETHYL)AMINO]-2-OXOETHYL}-2-HYDROXYBUTANEDIOIC ACID, ACSD, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Schmelz, S, Challis, G.L, Naismith, J.H. 登録日 2010-01-25 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme Acsd. J.Mol.Biol., 412, 2011
2EXN	Solution structure for the protein coded by gene locus BB0938 of Bordetella bronchiseptica. Northeast Structural Genomics target BoR11. 分子名称: Hypothetical protein BoR11 著者 Rossi, P, Ramelot, T, Xiao, R, Ho, C.K, Ma, L.-C, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2005-11-08 公開日 2005-11-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 (1)H, (13)C, and (15)N Resonance Assignments for the Protein Coded by Gene Locus BB0938 of Bordetella bronchiseptica J.Biomol.NMR, 33, 2005
3ZLP	Crystal structure of Schistosoma mansoni Peroxiredoxin 1 C48P mutant form with four decamers in the asymmetric unit 分子名称: THIOREDOXIN PEROXIDASE 著者 Saccoccia, F, Angelucci, F, Ardini, M, Boumis, G, Brunori, M, DiLeandro, L, Ippoliti, R, Miele, A.E, Natoli, G, Scotti, S, Bellelli, A. 登録日 2013-02-04 公開日 2013-09-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.515 Å) 主引用文献 Switching between the Alternative Structures and Functions of a 2-Cys Peroxiredoxin, by Site-Directed Mutagenesis J.Mol.Biol., 425, 2013
1HUM	SOLUTION STRUCTURE OF THE CHEMOKINE HMIP-1BETA(SLASH)ACT-2 BY MULTI-DIMENSIONAL NMR: A NOVEL CHEMOKINE DIMER 分子名称: HUMAN MACROPHAGE INFLAMMATORY PROTEIN 1 BETA 著者 Clore, G.M, Lodi, P.J, Garrett, D.S, Gronenborn, A.M. 登録日 1994-01-31 公開日 1994-04-30 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR. Science, 263, 1994
6NIY	A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex 分子名称: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. 登録日 2019-01-02 公開日 2019-01-23 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
6NCF	The structure of Stable-5-Lipoxygenase bound to AKBA 分子名称: (3alpha,8alpha,17alpha,18alpha)-3-(acetyloxy)-11-oxours-12-en-23-oic acid, Arachidonate 5-lipoxygenase, FE (II) ION 著者 Newcomer, M.E, Gilbert, N.C, Neau, D.B. 登録日 2018-12-11 公開日 2020-05-13 最終更新日 2020-07-08 実験手法 X-RAY DIFFRACTION (2.871 Å) 主引用文献 Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nat.Chem.Biol., 16, 2020

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