3OZJ
Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1
Summary for 3OZJ
Entry DOI | 10.2210/pdb3ozj/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, SRC-1, peptide of Nuclear receptor coactivator 2, (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate, ... (4 entities in total) |
Functional Keywords | nuclear receptor ligand-binding domain, ligand-binding and transactivation, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P19793 Q15596 |
Total number of polymer chains | 4 |
Total formula weight | 56755.81 |
Authors | |
Primary citation | Zhang, H.,Li, L.,Chen, L.,Hu, L.,Jiang, H.,Shen, X. Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode J.Mol.Biol., 407:13-20, 2011 Cited by PubMed: 21262235DOI: 10.1016/j.jmb.2011.01.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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