3OZJ

Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Retinoic acid receptor RXR-alpha	polymer	238	26667.9	2	UniProt (P19793) Pfam (PF00104) In PDB	Homo sapiens (human)	Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha
2	B, D	SRC-1, peptide of Nuclear receptor coactivator 2	polymer	11	1405.7	2	UniProt (Q15596) In PDB	Homo sapiens	NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3	A, C	(3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate	non-polymer		304.3	2	Chemie (BGV)
4		water	water		18.0	53	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56147.1
Non-Polymers*	Number of molecules	2
	Total formula weight	608.7
All*	Total formula weight	56755.8

*Water molecules are not included.