3OZJ
Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Retinoic acid receptor RXR-alpha | polymer | 238 | 26667.9 | 2 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha |
| 2 | B, D (B, D) | SRC-1, peptide of Nuclear receptor coactivator 2 | polymer | 11 | 1405.7 | 2 | UniProt (Q15596) | Homo sapiens | NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2 |
| 3 | E, F (A, C) | (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate | non-polymer | 304.3 | 2 | Chemie (BGV) PubChem (23332) PubChem (44461010) PubChem (45783102) PubChem (98952) PubChem (442142) PubChem (442272) PubChem (73759124) PubChem (3080597) PubChem (11370158) PubChem (12299966) PubChem (162962581) PubChem (162962582) PubChem (162962583) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56147.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 608.7 | |
| All* | Total formula weight | 56755.8 |
