PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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1CM4	Motions of calmodulin-four-conformer refinement 分子名称: CALCIUM ION, CALMODULIN, CALMODULIN-DEPENDENT PROTEIN KINASE II-ALPHA 著者 Wall, M.E, Phillips Jr, G.N. 登録日 1997-09-23 公開日 1998-03-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Motions of calmodulin characterized using both Bragg and diffuse X-ray scattering. Structure, 5, 1997
4MVW	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1433) 分子名称: 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4MWE	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-3-(prop-2-en-1-yl)-2-(prop-2-en-1-yloxy)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1475) 分子名称: 1-(3-{[5-chloro-3-(prop-2-en-1-yl)-2-(prop-2-en-1-yloxy)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
5QHW	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000347a 分子名称: 2-methyl-~{N}-(2-methylpropyl)imidazo[1,2-a]pyridine-3-carboxamide, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Schuller, M, Talon, R, Krojer, T, Brandao-Neto, J, Douangamath, A, Zhang, R, von Delft, F, Schuler, H, Kessler, B, Knapp, S, Bountra, C, Arrowsmith, C.H, Edwards, A, Elkins, J. 登録日 2018-05-21 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
4ZN7	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Diethylstilbestrol 分子名称: DIETHYLSTILBESTROL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. 登録日 2015-05-04 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.934 Å) 主引用文献 Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
3ZLC	Crystal Structure of Erv41p 分子名称: ER-DERIVED VESICLES PROTEIN ERV41 著者 Biterova, E.I, Svard, M, Possner, D.D.D, Guy, J.E. 登録日 2013-01-30 公開日 2013-03-27 最終更新日 2013-06-12 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 The Crystal Structure of the Lumenal Domain of Erv41P, a Protein Involved in Transport between the Endoplasmic Reticulum and Golgi Apparatus J.Mol.Biol., 425, 2013
4C0Z	The N-terminal domain of the Streptococcus pyogenes pilus tip adhesin Cpa 分子名称: ANCILLARY PROTEIN 2, CHLORIDE ION, GLYCEROL, ... 著者 Linke-Winnebeck, C, Paterson, N, Baker, E.N. 登録日 2013-08-08 公開日 2013-11-20 最終更新日 2014-01-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Model for the Covalent Adhesion of the Streptococcus Pyogenes Pilus Through a Thioester Bond. J.Biol.Chem., 289, 2014
3OZ5	S-Methyl Carbocyclic LNA 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(UMX)P*AP*CP*GP*C)-3'), SPERMINE 著者 Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E. 登録日 2010-09-24 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. J.Am.Chem.Soc., 132, 2010
5O5G	Robo1 Ig1 to 4 crystal form 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 1 著者 Aleksandrova, N, Gutsche, I, Kandiah, E, Avilov, S.V, Petoukhov, M.V, Seiradake, E, McCarthy, A.A. 登録日 2017-06-01 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Robo1 Forms a Compact Dimer-of-Dimers Assembly. Structure, 26, 2018
5O8A	Crystal Structure of rsEGFP2 in the non-fluorescent off-state determined by SFX 分子名称: Green fluorescent protein 著者 Coquelle, N, Sliwa, M, Woodhouse, J, Schiro, G, Adam, V, Aquila, A, Barends, T.R.M, Boutet, S, Byrdin, M, Carbajo, S, De la Mora, E, Doak, R.B, Feliks, M, Fieschi, F, Foucar, L, Guillon, V, Hilpert, M, Hunter, M, Jakobs, S, Koglin, J.E, Kovacsova, G, Lane, T.J, Levy, B, Liang, M, Nass, K, Ridard, J, Robinson, J.S, Roome, C.M, Ruckebusch, C, Seaberg, M, Thepaut, M, Cammarata, M, Demachy, I, Field, M, Shoeman, R.L, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M. 登録日 2017-06-12 公開日 2017-09-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography. Nat Chem, 10, 2018
4Z3S	Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 3'-deoxy-3'-{[(2E)-3-(4-{[(4Z)-6-O-(6-deoxy-3,4-di-O-methyl-alpha-D-mannopyranosyl)-5-O-methyl-alpha-D-threo-hex-4-enofuranosyl]oxy}phenyl)-2-methylprop-2-enoyl]amino}-N,N-dimethyladenosine, ... 著者 Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. 登録日 2015-03-31 公開日 2015-06-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58, 2015
4N1X	Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin G 分子名称: OPEN FORM - PENICILLIN G, Peptidoglycan glycosyltransferase 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) 登録日 2013-10-04 公開日 2013-10-30 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin G To be Published
4EON	Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with the inhibitor RO3306 分子名称: (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ... 著者 Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. 登録日 2012-04-14 公開日 2013-02-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
4EOR	Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor NU6102 分子名称: Cyclin-A2, Cyclin-dependent kinase 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE 著者 Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. 登録日 2012-04-14 公開日 2013-02-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
1KUJ	Crystal structure of Jacalin complexed with 1-O-methyl-alpha-D-mannose 分子名称: JACALIN ALPHA CHAIN, JACALIN BETA CHAIN, methyl alpha-D-mannopyranoside 著者 Bourne, Y, Astoul, C.H, Zamboni, V, Peumans, W.J, Menu-Bouaouiche, L, Van Damme, E.J.M, Barre, A, Rouge, P. 登録日 2002-01-22 公開日 2002-06-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. Biochem.J., 364, 2002
3ZSF	Crystal structure of the L-cystine solute receptor of Neisseria gonorrhoeae in the unliganded open conformation 分子名称: ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID 著者 Bulut, H, Moniot, S, Scheffel, F, Gathmann, S, Licht, A, Saenger, W, Schneider, E. 登録日 2011-06-27 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae. J.Mol.Biol., 415, 2012
4EQ5	DNA ligase from the archaeon Thermococcus sibiricus 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 著者 Petrova, T, Bezsudnova, E.Y, Dorokhov, B.D, Slutskaya, E.S, Polyakov, K.M, Dorovatovskiy, P.V, Ravin, N.V, Skryabin, K.G, Kovalchuk, M.V, Popov, V.O. 登録日 2012-04-18 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Expression, purification, crystallization and preliminary crystallographic analysis of a thermostable DNA ligase from the archaeon Thermococcus sibiricus. Acta Crystallogr.,Sect.F, 68, 2012
2V91	STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE 分子名称: METHYL (2S,3R,4S)-3-ETHYL-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-[(1S)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-1-YLMETHYL]-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE, STRICTOSIDINE SYNTHASE 著者 Loris, E.A, Panjikar, S, Ruppert, M, Barleben, L, Unger, M, Stoeckigt, J. 登録日 2007-08-16 公開日 2008-09-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structure Based Engineering of Strictosidine Synthase: Auxiliary for Alkaloid Libraries Chem.Biol., 14, 2007
3OID	Crystal Structure of Enoyl-ACP Reductases III (FabL) from B. subtilis (complex with NADP and TCL) 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRICLOSAN 著者 Kim, K.-H, Ha, B.H, Kim, S.J, Hong, S.K, Hwang, K.Y, Kim, E.E. 登録日 2010-08-19 公開日 2011-01-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406, 2011
1FY1	[R23S,F25E]HBP, A MUTANT OF HUMAN HEPARIN BINDING PROTEIN (CAP37) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHANOL, ... 著者 Kastrup, J.S, Linde, V, Pedersen, A.K, Stoffer, B, Iversen, L.F, Larsen, I.K, Rasmussen, P.B, Flodgaard, H.J, Bjorn, S.E. 登録日 2000-09-28 公開日 2001-09-28 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding. Proteins, 42, 2001
2NX5	Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A 分子名称: Beta-2-microglobulin, EBV peptide, EPLPQGQLTAY, ... 著者 Tynan, F.E, Reid, H.H, Rossjohn, J. 登録日 2006-11-16 公開日 2007-02-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule Nat.Immunol., 8, 2007
6DV6	Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state 分子名称: Protein InvG 著者 Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J. 登録日 2018-06-22 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin. Nat Commun, 9, 2018
6N45	Crystal structure of the cryptic polo box domain of human activated Plk4 variant 1 分子名称: Chimera protein of Serine/threonine-protein kinase PLK4 and DDB1- and CUL4-associated factor 1 著者 Zhang, L, Park, J.-E, Meng, L, Lee, K.S. 登録日 2018-11-17 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis. Nat Commun, 10, 2019
6DD5	Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein 分子名称: GLYCEROL, MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, SULFATE ION, ... 著者 Stamos, J.L, Mohr, G, Silas, S, Makarova, K.S, Markham, L.M, Yao, J, Lucas-Elio, P, Sanchez-Amat, A, Fire, A.Z, Koonin, E.V, Lambowitz, A.M. 登録日 2018-05-09 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol. Cell, 72, 2018
1KLI	Cofactor-and substrate-assisted activation of factor VIIa 分子名称: BENZAMIDINE, CALCIUM ION, GLYCEROL, ... 著者 Sichler, K, Banner, D.W, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H. 登録日 2001-12-12 公開日 2002-09-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal Structure of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions J.Mol.Biol., 322, 2002

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