6DD5

Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein

Summary for 6DD5

Entry DOI	10.2210/pdb6dd5/pdb
Related PRD ID	PRD_900001
Descriptor	MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, GLYCEROL, ... (4 entities in total)
Functional Keywords	crispr cas protein, endoribonuclease, hydrolase
Biological source	Escherichia coli O157:H7 More
Total number of polymer chains	2
Total formula weight	153068.14
Authors	Stamos, J.L.,Mohr, G.,Silas, S.,Makarova, K.S.,Markham, L.M.,Yao, J.,Lucas-Elio, P.,Sanchez-Amat, A.,Fire, A.Z.,Koonin, E.V.,Lambowitz, A.M. (deposition date: 2018-05-09, release date: 2018-10-17, Last modification date: 2023-10-11)
Primary citation	Mohr, G.,Silas, S.,Stamos, J.L.,Makarova, K.S.,Markham, L.M.,Yao, J.,Lucas-Elio, P.,Sanchez-Amat, A.,Fire, A.Z.,Koonin, E.V.,Lambowitz, A.M. A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol. Cell, 72:700-, 2018 Cited by PubMed: 30344094 DOI: 10.1016/j.molcel.2018.09.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation