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7QWQ
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BU of 7qwq by Molmil
Ternary complex of ribosome nascent chain with SRP and NAC
分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E.
登録日2022-01-25
公開日2022-03-16
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
8P2K
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BU of 8p2k by Molmil
Ternary complex of translating ribosome, NAC and METAP1
分子名称: 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N.
登録日2023-05-16
公開日2023-07-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献NAC controls cotranslational N-terminal methionine excision in eukaryotes.
Science, 380, 2023
7W59
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BU of 7w59 by Molmil
The cryo-EM structure of human pre-C*-I complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
6ICZ
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BU of 6icz by Molmil
Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhang, X, Zhan, X, Yan, C, Shi, Y.
登録日2018-09-07
公開日2019-03-13
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
7W5B
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BU of 7w5b by Molmil
The cryo-EM structure of human C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
6ID0
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BU of 6id0 by Molmil
Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ...
著者Zhang, X, Zhan, X, Yan, C, Shi, Y.
登録日2018-09-07
公開日2019-03-13
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ID1
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BU of 6id1 by Molmil
Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ...
著者Zhang, X, Zhan, X, Yan, C, Shi, Y.
登録日2018-09-07
公開日2019-03-13
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
7S9P
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BU of 7s9p by Molmil
Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dCTP analog
分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Freudenthal, B.D, Ryan, B.J, Smith, M.R.
登録日2021-09-21
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc., 144, 2022
7S9Q
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BU of 7s9q by Molmil
Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog
分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Freudenthal, B.D, Ryan, B.J, Smith, M.R.
登録日2021-09-21
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc., 144, 2022
4R5P
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BU of 4r5p by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) with DNA and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor
分子名称: 5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', 5'-D(*TP*GP*GP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3', HIV-1 reverse transcriptase, ...
著者Das, K, Martinez, S.E, Arnold, E.
登録日2014-08-21
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.
Proc.Natl.Acad.Sci.USA, 112, 2015
8Q7W
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BU of 8q7w by Molmil
Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-17
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024
8Q7X
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BU of 8q7x by Molmil
Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-17
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024
8Q7V
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BU of 8q7v by Molmil
Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-17
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024
8Q7Q
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BU of 8q7q by Molmil
Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-16
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
分子名称: RNA-binding protein FUS, Transportin-1
著者Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
登録日2017-11-25
公開日2018-05-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
7AQO
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BU of 7aqo by Molmil
yeast THO-Sub2 complex dimer
分子名称: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-22
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
3EVA
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BU of 3eva by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVG
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BU of 3evg by Molmil
Crystal structure of Dengue-2 virus methyltransferase complexed with S-adenosyl-L-homocysteine
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
5SUQ
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BU of 5suq by Molmil
Crystal structure of the THO-Sub2 complex
分子名称: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ...
著者Ren, Y, Blobel, G.
登録日2016-08-03
公開日2017-01-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
3EVB
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BU of 3evb by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
2HUA
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BU of 2hua by Molmil
Solution Structure of CSFV IRES Domain IIa
分子名称: CSFV IRES Domain IIa
著者Locker, N, Easton, L.E, Lukavsky, P.J.
登録日2006-07-26
公開日2007-04-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly.
Embo J., 26, 2007
7PRE
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BU of 7pre by Molmil
Solution structure of the NRDI domain of Nab3
分子名称: HLJ1_G0022400.mRNA.1.CDS.1
著者Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M.
登録日2021-09-21
公開日2022-01-12
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis of Nrd1-Nab3 heterodimerization.
Life Sci Alliance, 5, 2022
7Z27
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BU of 7z27 by Molmil
Crystal structure of the SPOC domain of human RBM15
分子名称: RNA-binding protein 15
著者Grishkovskaya, I, Appel, L.M, Djinovic-Carugo, K, Slade, D.
登録日2022-02-25
公開日2022-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
3PMN
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BU of 3pmn by Molmil
ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 5'-D(*CP*AP*GP*TP*AP*G)-3', 5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3', ...
著者Bebenek, K, Pedersen, L.C, Kunkel, T.A.
登録日2010-11-17
公開日2011-02-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Replication infidelity via a mismatch with Watson-Crick geometry.
Proc.Natl.Acad.Sci.USA, 108, 2011
1NBS
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BU of 1nbs by Molmil
Crystal structure of the specificity domain of Ribonuclease P RNA
分子名称: LEAD (II) ION, MAGNESIUM ION, RIBONUCLEASE P RNA
著者Krasilnikov, A.S, Yang, X, Pan, T, Mondragon, A.
登録日2002-12-03
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structure of the specificity domain of Ribonuclease P
Nature, 421, 2003

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件を2024-08-07に公開中

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