PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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3Q8X	Structure of a toxin-antitoxin system bound to its substrate 分子名称: Antidote of epsilon-zeta postsegregational killing system, SULFATE ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... 著者 Mutschler, H, Gebhardt, M, Shoeman, R.L, Meinhart, A. 登録日 2011-01-07 公開日 2011-03-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. Plos Biol., 9, 2011
3U9E	The crystal structure of a possible phosphate acetyl/butaryl transferase (from Listeria monocytogenes EGD-e) in complex with CoA. 分子名称: ARGININE, CHLORIDE ION, COENZYME A, ... 著者 Tan, K, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-10-18 公開日 2011-11-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 The crystal structure of a possible phosphate acetyl/butaryl transferase (from Listeria monocytogenes EGD-e) in complex with CoA. To be Published
4KZC	Structure of PI3K gamma with Imidazopyridine inhibitors 分子名称: N-{6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridin-2-yl}acetamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Knapp, M.S, Elling, E.A. 登録日 2013-05-29 公開日 2013-07-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K. Bioorg.Med.Chem.Lett., 23, 2013
1JKM	BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE 分子名称: BREFELDIN A ESTERASE 著者 Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S. 登録日 1998-02-04 公開日 1999-02-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase. Nat.Struct.Biol., 6, 1999
4KVN	Crystal structure of Fab 39.29 in complex with Influenza Hemagglutinin A/Perth/16/2009 (H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Fong, R, Swem, L.R, Lupardus, P.J. 登録日 2013-05-22 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Novel In vivo Human Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Anti-Influenza A Antibodies Cell Host Microbe, 14, 2013
1TMB	MOLECULAR BASIS FOR THE INHIBITION OF HUMAN ALPHA-THROMBIN BY THE MACROCYCLIC PEPTIDE CYCLOTHEONAMIDE A 分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ... 著者 Qiu, X, Padmanabhan, K.P, Maryanoff, B.E, Tulinsky, A. 登録日 1993-05-27 公開日 1994-01-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A. Proc.Natl.Acad.Sci.USA, 90, 1993
1VY7	Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Polikanov, Y.S, Steitz, T.A, Innis, C.A. 登録日 2014-05-13 公開日 2014-08-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
1VY6	Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Polikanov, Y.S, Steitz, T.A, Innis, C.A. 登録日 2014-05-13 公開日 2014-08-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
1M4L	STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION 分子名称: CARBOXYPEPTIDASE A, ZINC ION 著者 Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G. 登録日 2002-07-03 公開日 2003-01-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Refined structure of bovine carboxypeptidase A at 1.25 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
1ESF	STAPHYLOCOCCAL ENTEROTOXIN A 分子名称: CADMIUM ION, STAPHYLOCOCCAL ENTEROTOXIN A 著者 Schad, E.M, Svensson, L.A. 登録日 1995-05-25 公開日 1996-07-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the superantigen staphylococcal enterotoxin type A. EMBO J., 14, 1995
3V6E	Crystal Structure of USP2 and a mutant form of Ubiquitin 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ... 著者 Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2011-12-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
2YET	Thermoascus GH61 isozyme A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL GROUP, COPPER (II) ION, ... 著者 Otten, H, Quinlan, R.J, Sweeney, M.D, Poulsen, J.-C.N, Johansen, K.S, Krogh, K.B.R.M, Joergensen, C.I, Tovborg, M, Anthonsen, A, Tryfona, T, Walter, C.P, Dupree, P, Xu, F, Davies, G.J, Walton, P.H, Lo Leggio, L. 登録日 2011-03-30 公開日 2011-09-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Insights Into the Oxidative Degradation of Cellulose by a Copper Metalloenzyme that Exploits Biomass Components. Proc.Natl.Acad.Sci.USA, 108, 2011
1SJF	Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution 分子名称: COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A 著者 Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. 登録日 2004-03-03 公開日 2004-05-18 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 A conformational switch controls hepatitis delta virus ribozyme catalysis. Nature, 429, 2004
4LUN	Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons 分子名称: CHLORIDE ION, Nonsense-mediated mRNA decay protein 2 著者 Fourati, Z, Roy, B, Millan, C, Courreux, P.D, Kervestin, S, van Tilbeurgh, H, He, F, Uson, I, Jacobson, A, Graille, M. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.641 Å) 主引用文献 A highly conserved region essential for NMD in the Upf2 N-terminal domain. J.Mol.Biol., 426, 2014
2BXR	Human Monoamine Oxidase A in complex with Clorgyline, Crystal Form A 分子名称: AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE 著者 De Colibus, L, Binda, C, Edmondson, D.E, Mattevi, A. 登録日 2005-07-27 公開日 2005-08-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B Proc.Natl.Acad.Sci.USA, 102, 2005
1U67	Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms Predominantly 11-HPETE. 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARACHIDONIC ACID, PROTOPORPHYRIN IX CONTAINING CO, ... 著者 Harman, C.A, Rieke, C.J, Garavito, R.M, Smith, W.L. 登録日 2004-07-29 公開日 2004-09-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of arachidonic Acid bound to a mutant of prostaglandin endoperoxide h synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic Acid. J.Biol.Chem., 279, 2004
2C69	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: (5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE, CELL DIVISION PROTEIN KINASE 2 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-08 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg. Med. Chem. Lett., 16, 2006
2ISG	Botulinum Neurotoxin A Light Chain WT Crystal Form B 分子名称: NICKEL (II) ION, Neurotoxin BoNT/A, ZINC ION 著者 Brunger, A.T, Stegmann, C.M. 登録日 2006-10-17 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J.Biol.Chem., 282, 2007
8VKC	Crystal structure of dehaloperoxidase A in complex with substrate 4-nitrophenol 分子名称: Dehaloperoxidase A, GLYCEROL, P-NITROPHENOL, ... 著者 Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. 登録日 2024-01-08 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 2024
8VSK	Crystal structure of Dehaloperoxidase A in complex with substrate 2,4-dibromophenol 分子名称: 2,4-bis(bromanyl)phenol, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase A, ... 著者 Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. 登録日 2024-01-24 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.515 Å) 主引用文献 Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 2024
8VKD	Crystal structure of dehaloperoxidase A in complex with substrate 4-nitrocatechol 分子名称: 4-NITROCATECHOL, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. 登録日 2024-01-08 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 2024
3T9T	Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline 分子名称: (2Z)-4-(dimethylamino)-N-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-N-methylbut-2-enamide, GLYCEROL, Tyrosine-protein kinase ITK/TSK 著者 Han, S, Caspers, N. 登録日 2011-08-03 公開日 2011-10-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis. Bioorg.Med.Chem.Lett., 21, 2011
1SJ3	Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound 分子名称: MAGNESIUM ION, precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A 著者 Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A. 登録日 2004-03-02 公開日 2004-05-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Conformational Switch controls hepatitis delta virus ribozyme catalysis Nature, 429, 2004
8VZR	Crystal structure of dehaloperoxidase A in complex with substrate 4-bromo-o-cresol 分子名称: 4-bromo-2-methylphenol, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase A, ... 著者 Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. 登録日 2024-02-12 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 2024
1S1S	Crystal Structure of ZipA in complex with indoloquinolizin 10b 分子名称: Cell division protein zipA, N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide 著者 Jennings, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenny, C.H, Moghazeh, S.L, Petersen, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G. 登録日 2004-01-07 公開日 2005-01-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction BIOORG.MED.CHEM.LETT., 14, 2004

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