1U67

Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms Predominantly 11-HPETE.

Summary for 1U67

Entry DOI	10.2210/pdb1u67/pdb
Related	1diy
Descriptor	Prostaglandin G/H synthase 1 precursor, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	cyclooxgenase, arachidonic acid, heme, eicosanoid, 11-hete, cox-1, cox-2, oxidoreductase
Biological source	Ovis aries (sheep)
Total number of polymer chains	1
Total formula weight	72475.02
Authors	Harman, C.A.,Rieke, C.J.,Garavito, R.M.,Smith, W.L. (deposition date: 2004-07-29, release date: 2004-09-07, Last modification date: 2023-08-23)
Primary citation	Harman, C.A.,Rieke, C.J.,Garavito, R.M.,Smith, W.L. Crystal structure of arachidonic Acid bound to a mutant of prostaglandin endoperoxide h synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic Acid. J.Biol.Chem., 279:42929-42935, 2004 Cited by PubMed: 15292194 DOI: 10.1074/jbc.M403013200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation