Structure of a toxin-antitoxin system bound to its substrate

Summary for 3Q8X

Related1GVN 2P5T
DescriptorAntidote of epsilon-zeta postsegregational killing system, Zeta-toxin, SULFATE ION, ... (4 entities in total)
Functional Keywordspolynucleotide kinase fold, epsilon: antidote zeta: bacterial toxin, transferase
Biological sourceStreptococcus pyogenes
Total number of polymer chains4
Total molecular weight87157.85
Mutschler, H.,Gebhardt, M.,Shoeman, R.L.,Meinhart, A. (deposition date: 2011-01-07, release date: 2011-03-09, Last modification date: 2019-07-17)
Primary citation
Mutschler, H.,Gebhardt, M.,Shoeman, R.L.,Meinhart, A.
A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis.
Plos Biol., 9:e1001033-e1001033, 2011
PubMed: 21445328 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pbio.1001033
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2563 0.1% 1.2% 0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution