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3A33
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BU of 3a33 by Molmil
UbcH5b~Ubiquitin Conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K.
登録日2009-06-08
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates
Structure, 18, 2010
5MNJ
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BU of 5mnj by Molmil
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
分子名称: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ...
著者Klejnot, M, Huang, D.T.
登録日2016-12-13
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017
6IF1
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BU of 6if1 by Molmil
Crystal structure of Ube2K and K48-linked di-ubiquitin complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Lim, J.J, Eom, S.H.
登録日2018-09-18
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.466 Å)
主引用文献Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis.
Biochem. Biophys. Res. Commun., 506, 2018
5TUT
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BU of 5tut by Molmil
UbcH5a-Ub isopeptide conjugate
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D1
著者Sanchez, J.G, Wagner, J.M, Pornillos, O.
登録日2016-11-07
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献UbcH5a-Ub isopeptide conjugate
To be Published
2YHO
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BU of 2yho by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
分子名称: ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
6ZHS
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BU of 6zhs by Molmil
Uba1 bound to two E2 (Ubc13) molecules
分子名称: GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ...
著者Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
5ULH
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BU of 5ulh by Molmil
Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
6CP2
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BU of 6cp2 by Molmil
SidC in complex with UbcH7~Ub
分子名称: Polyubiquitin-B, SidC, Ubiquitin-conjugating enzyme E2 L3
著者Wasilko, D.J, Huang, Q, Mao, Y.
登録日2018-03-13
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
6CP0
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BU of 6cp0 by Molmil
SdcA in complex with the E2, UbcH5C
分子名称: SdcA, Ubiquitin-conjugating enzyme E2 D3
著者Wasilko, D.J, Huang, Q, Mao, Y.
登録日2018-03-13
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
2VRR
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BU of 2vrr by Molmil
Structure of SUMO modified Ubc9
分子名称: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ...
著者Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A.
登録日2008-04-13
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Ubc9 sumoylation regulates SUMO target discrimination.
Mol. Cell, 31, 2008
5ULK
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BU of 5ulk by Molmil
Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
6ZHT
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BU of 6zht by Molmil
Uba1-Ubc13 disulfide mediated complex
分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ...
著者Schaefer, A, Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
6ZHU
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BU of 6zhu by Molmil
Yeast Uba1 in complex with Ubc3 and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ...
著者Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system
To Be Published
5ULF
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BU of 5ulf by Molmil
Crystal Structure of a UbcH5b~Ub conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
7AI0
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BU of 7ai0 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.559 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
7AI1
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BU of 7ai1 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
7AHZ
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BU of 7ahz by Molmil
Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
2XWU
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BU of 2xwu by Molmil
CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX
分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9
著者Gruenwald, M, Bono, F.
登録日2010-11-05
公開日2010-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation.
Embo J., 30, 2011
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5NKZ
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BU of 5nkz by Molmil
Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p
分子名称: Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa
著者Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C.
登録日2017-04-03
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
2Y9P
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BU of 2y9p by Molmil
Pex4p-Pex22p mutant II structure
分子名称: PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA
著者Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M.
登録日2011-02-16
公開日2012-02-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Pex4P-Pex22P Structure
To be Published
6JKY
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BU of 6jky by Molmil
Crystal structure of MvcA-UBE2N-Ub complex from Legionella pneumophila
分子名称: MvcA, Ub, Ubiquitin-conjugating enzyme E2 N
著者Ouyang, S.Y, Guan, H.
登録日2019-03-03
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.454 Å)
主引用文献Legionella pneumophila regulates the activity of UBE2N by deamidase-mediated deubiquitination.
Embo J., 39, 2020
6D4P
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BU of 6d4p by Molmil
Ube2D1 in complex with ubiquitin variant Ubv.D1.1
分子名称: Ubiquitin Variant Ubv.D1.1, Ubiquitin-conjugating enzyme E2 D1
著者Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F.
登録日2018-04-18
公開日2019-07-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020
6JB6
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BU of 6jb6 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
To Be Published
6D68
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BU of 6d68 by Molmil
Ube2G1 in complex with ubiquitin variant Ubv.G1.1
分子名称: Ubiquitin-conjugating enzyme E2 G1, Ubv.G1.1
著者Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F.
登録日2018-04-20
公開日2019-07-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020

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