Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4Z0R
DownloadVisualize
BU of 4z0r by Molmil
Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide
分子名称: 1,2-ETHANEDIOL, Histone H3.1, SULFATE ION, ...
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-03-26
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide
To be Published
3MUL
DownloadVisualize
BU of 3mul by Molmil
Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Peptide of Histone H3.3
著者Vollmuth, F, Geyer, M.
登録日2010-05-03
公開日2010-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3MUK
DownloadVisualize
BU of 3muk by Molmil
Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, peptide of Histone H3.3
著者Vollmuth, F, Geyer, M.
登録日2010-05-03
公開日2010-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3U78
DownloadVisualize
BU of 3u78 by Molmil
E67-2 selectively inhibits KIAA1718, a human histone H3 lysine 9 Jumonji demethylase
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, ...
著者Upadhyay, A.K, Cheng, X.
登録日2011-10-13
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases.
J.Mol.Biol., 416, 2012
4PY5
DownloadVisualize
BU of 4py5 by Molmil
Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA
分子名称: 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', GLYCEROL, ...
著者Figiel, M, Nowotny, M.
登録日2014-03-26
公開日2014-07-30
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.
Nucleic Acids Res., 42, 2014
3MEA
DownloadVisualize
BU of 3mea by Molmil
Crystal structure of the SGF29 in complex with H3K4me3
分子名称: Histone H3, SAGA-associated factor 29 homolog
著者Bian, C, Xu, C, Tempel, W, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3ME9
DownloadVisualize
BU of 3me9 by Molmil
Crystal structure of SGF29 in complex with H3K4me3 peptide
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C, Tempel, W, Xu, C, Guo, Y, Dong, A, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MET
DownloadVisualize
BU of 3met by Molmil
Crystal structure of SGF29 in complex with H3K4me2
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEU
DownloadVisualize
BU of 3meu by Molmil
Crystal structure of SGF29 in complex with H3R2me2sK4me3
分子名称: Histone H3, SAGA-associated factor 29 homolog, SULFATE ION
著者Bian, C.B, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEV
DownloadVisualize
BU of 3mev by Molmil
Crystal structure of SGF29 in complex with R2AK4me3
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
6L49
DownloadVisualize
BU of 6l49 by Molmil
H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (18.9 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
6L4A
DownloadVisualize
BU of 6l4a by Molmil
H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
4UUZ
DownloadVisualize
BU of 4uuz by Molmil
MCM2-histone complex
分子名称: DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4
著者Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F.
登録日2014-08-01
公開日2015-02-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork.
Nucleic Acids Res., 43, 2015
1M1D
DownloadVisualize
BU of 1m1d by Molmil
TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR
分子名称: HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE
著者Poux, A.N, Cebrat, M, Kim, C.M, Cole, P.A, Marmorstein, R.
登録日2002-06-18
公開日2002-10-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor.
Proc.Natl.Acad.Sci.USA, 99, 2002
7LHY
DownloadVisualize
BU of 7lhy by Molmil
Caenorhabditis elegans SWSN-4 (SMARCA4-BRG1) ATPase Bromodomain in complex with a modified histone H3, N6-epsilon-acetyl-L-lysine 14 (H3K14ac) polypeptide
分子名称: H3(7-20)K14ac, SWI/SNF nucleosome remodeling complex component
著者Enriquez, P, Rose, R.B.
登録日2021-01-26
公開日2021-09-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14.
J.Biol.Chem., 297, 2021
2KGI
DownloadVisualize
BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-12
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2H2G
DownloadVisualize
BU of 2h2g by Molmil
The Structural Basis of Sirtuin substrate affinity
分子名称: HISTONE H3 PEPTIDE, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-11-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
6KMJ
DownloadVisualize
BU of 6kmj by Molmil
Crystal structure of Sth1 bromodomain in complex with H3K14Ac
分子名称: GLYCEROL, Histone H3, Nuclear protein STH1/NPS1
著者Chen, G, Li, W, Yan, F, Wang, D, Chen, Y.
登録日2019-07-31
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex.
Structure, 28, 2020
3Q33
DownloadVisualize
BU of 3q33 by Molmil
Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, HISTONE H3, ...
著者Tang, Y, Yuan, H, Meeth, K, Marmorstein, R.
登録日2010-12-21
公開日2011-02-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
2RNW
DownloadVisualize
BU of 2rnw by Molmil
The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the Human Transcriptional Co-Activators PCAf and CBP
分子名称: Histone H3, Histone acetyltransferase PCAF
著者Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M.
登録日2008-02-03
公開日2008-05-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16, 2008
2RNX
DownloadVisualize
BU of 2rnx by Molmil
The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP
分子名称: Histone H3, Histone acetyltransferase PCAF
著者Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M.
登録日2008-02-03
公開日2008-05-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16, 2008
1WZ1
DownloadVisualize
BU of 1wz1 by Molmil
Crystal structure of the Fv fragment complexed with dansyl-lysine
分子名称: Ig heavy chain, Ig light chain, N~6~-{[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}-L-LYSINE
著者Nakasako, M, Oka, T, Mashumo, M, Takahashi, H, Shimada, I, Yamaguchi, Y, Kato, K, Arata, Y.
登録日2005-02-21
公開日2006-01-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational dynamics of complementarity-determining region H3 of an anti-dansyl Fv fragment in the presence of its hapten
J.Mol.Biol., 351, 2005
2FSA
DownloadVisualize
BU of 2fsa by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
分子名称: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor
著者Li, H, Patel, D.J.
登録日2006-01-21
公開日2006-07-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3TW1
DownloadVisualize
BU of 3tw1 by Molmil
Structure of Rtt106-AHN
分子名称: GLYCEROL, Histone chaperone RTT106, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE
著者Su, D, Thompson, J.R, Mer, G.
登録日2011-09-21
公開日2012-02-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
5X60
DownloadVisualize
BU of 5x60 by Molmil
Crystal structure of LSD1-CoREST in complex with peptide 9
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
著者Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T.
登録日2017-02-20
公開日2017-04-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon