2RNW

The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the Human Transcriptional Co-Activators PCAf and CBP

Summary for 2RNW

• Entry DOI: 10.2210/pdb2rnw/pdb
• Related: 2RNX
• Descriptor: Histone acetyltransferase PCAF, Histone H3 (2 entities in total)
• Functional Keywords: bromodomain, histone, acetyltransferase, acyltransferase, cell cycle, host-virus interaction, nucleus, polymorphism, transcription, transcription regulation, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, phosphoprotein, transferase-nuclear protein complex, transferase/nuclear protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (By similarity): Q92831; Nucleus: P61830
• Total number of polymer chains: 2
• Total formula weight: 15659.05

Authors

Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (deposition date: 2008-02-03, release date: 2008-05-06, Last modification date: 2023-11-15)

• Primary citation: Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M.; Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300; Structure, 16:643-652, 2008; PubMed: 18400184; DOI: 10.1016/j.str.2008.01.010

Experimental method

SOLUTION NMR