2RNW
The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the Human Transcriptional Co-Activators PCAf and CBP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFmepvKrteap..GYYevIrfpMdlktMserlknry..Yvskklfmadlqr.VftNCkeY |
| Chain | Residue | Details |
| A | ALA745-TYR802 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 104 |
| Details | Domain: {"description":"Bromo","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"11742990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11751634","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11752412","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12152067","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12353038","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12845608","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15949446","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16122352","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16168379","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16185711","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"10911986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10975519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15719021","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
