4PY5

Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA

Summary for 4PY5

• Entry DOI: 10.2210/pdb4py5/pdb
• Descriptor: Ribonuclease, 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', ... (7 entities in total)
• Functional Keywords: rnase h fold, rna/dna hybrid, hydrolase-dna-rna complex, hydrolase/dna/rna
• Biological source: Thermovibrio ammonificans
• Cellular location: Cytoplasm (By similarity): E8T217
• Total number of polymer chains: 3
• Total formula weight: 42989.96

Authors

Figiel, M.,Nowotny, M. (deposition date: 2014-03-26, release date: 2014-07-30, Last modification date: 2014-10-29)

• Primary citation: Figiel, M.,Nowotny, M.; Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.; Nucleic Acids Res., 42:9285-9294, 2014; PubMed: 25016521; DOI: 10.1093/nar/gku615

Experimental method

X-RAY DIFFRACTION (2.1 Å)