PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7CYP	Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of HB27, ... 著者 Wang, X, Zhu, L. 登録日 2020-09-04 公開日 2021-06-09 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2. Natl Sci Rev, 8, 2021
8DT3	Cryo-EM structure of spike binding to Fab of neutralizing antibody (locally refined) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab of SW186, Light chain Fab of SW186, ... 著者 Sun, P.C, Fang, Y, Bai, X.C, Chen, Z.J. 登録日 2022-07-25 公開日 2022-08-03 最終更新日 2022-11-09 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif. Sci Immunol, 7, 2022
4ODT	Fab Structure of lipid A-specific antibody S1-15 in complex with lipid A carbohydrate backbone 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, S1-15 Fab (IgG2b kappa) light chain, ... 著者 Haji-Ghassemi, O, Evans, S.V. 登録日 2014-01-10 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
7RK2	Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution 分子名称: Capsid protein VP25, scFv 2D9 著者 Meyer, L, Cuellar, C, DuBois, R.M. 登録日 2021-07-21 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96, 2022
7RK1	Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 3E8, an astrovirus-neutralizing antibody, at 2.05-A resolution 分子名称: Capsid polyprotein VP70, scFv 3E8 著者 Meyer, L, DuBois, R.M. 登録日 2021-07-21 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96, 2022
6URH	Crystal structure of broadly neutralizing antibody AR3X in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR3X Heavy Chain, ... 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2019-10-23 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein. Elife, 9, 2020
6V4O	Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ... 著者 Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-11-28 公開日 2020-10-07 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity, 53, 2020
6V4N	Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ... 著者 Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-11-28 公開日 2020-10-07 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity, 53, 2020
6XSK	Cryo-EM Structure of Vaccine-Elicited Rhesus Antibody 789-203-3C12 in Complex with Stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 789-203-3C12 Fab Heavy Chain, ... 著者 Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. 登録日 2020-07-15 公開日 2021-07-21 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses. Immunity, 55, 2022
4ODS	Unliganded Fab structure of lipid A-specific antibody S55-3 分子名称: S55-3 Fab (IgG2b) heavy chain 著者 Haji-Ghassemi, O, Evans, S.V. 登録日 2014-01-10 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
7SJS	Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8 分子名称: ACETATE ION, CC40.8 Fab heavy chain, CC40.8 Fab light chain, ... 著者 Yuan, M, Wilson, I.A. 登録日 2021-10-18 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.612 Å) 主引用文献 A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Sci Transl Med, 14, 2022
7KPB	Human TNF-alpha TNFR1 complex bound to conformationally selective antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one, Fab1974 - Heavy Chain, ... 著者 Fox III, D, Conrady, D.G, Lowe, M, Ceska, T. 登録日 2020-11-10 公開日 2021-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF Nat Commun, 12, 2021
4ODU	Unliganded Fab structure of lipid A-specific antibody S1-15 分子名称: S1-15 Fab (IgG2b kappa) light chain, S1-15 Fab (IgG2b) heavy chain, SULFATE ION 著者 Haji-Ghassemi, O, Evans, S.V. 登録日 2014-01-10 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
4ODV	Fab Structure of lipid A-specific antibody A6 in complex with lipid A carbohydrate backbone 分子名称: 2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, A6 Fab (IgG2b kappa) light chain, A6 Fab (IgG2b) heavy chain, ... 著者 Haji-Ghassemi, O, Evans, S.V. 登録日 2014-01-10 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
6KYZ	HRV14 3C in complex with single chain antibody YDF 分子名称: Genome polyprotein, YDF H chain, YDF L chain 著者 Meng, B, Yang, B, Wilson, I.A. 登録日 2019-09-20 公開日 2020-05-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proc.Natl.Acad.Sci.USA, 117, 2020
8HGM	Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-11 Fab heavy chain, NIV-11 Fab light chain, ... 著者 Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. 登録日 2022-11-15 公開日 2023-10-25 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
8PWV	PfRH5 bound to monoclonal antibody MAD8-502 分子名称: Reticulocyte-binding protein homolog 5, monoclonal antibody MAD8-502 著者 Farrell, B, Higgins, M.K. 登録日 2023-07-21 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 PfRH5 bound to monoclonal antibody MAD8-502 To Be Published
8PWX	PfRH5 bound to monoclonal antibody R5.008 分子名称: GLYCEROL, Reticulocyte-binding protein homolog 5, scFv fragment for antibody R5.008 著者 Farrell, B, Higgins, M.K. 登録日 2023-07-21 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 PfRH5 bound to monoclonal antibody R5.008 To Be Published
8HGL	SARS-CoV-2 spike in complex with neutralizing antibody NIV-11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-11 Fab heavy chain, ... 著者 Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. 登録日 2022-11-15 公開日 2023-10-25 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
7RQQ	Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP 分子名称: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ... 著者 Hurlburt, N.K, Pancera, M. 登録日 2021-08-06 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
7RQP	Structure of PfCSP NPNV binding antibody L9 分子名称: L9 Heavy Chain, L9 Kappa Chain 著者 Hurlburt, N.K, Pancera, M. 登録日 2021-08-06 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
7RQR	Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP 分子名称: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ... 著者 Hurlburt, N.K, Pancera, M. 登録日 2021-08-06 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
8PWW	PfRH5 bound to monoclonal antibody MAD8-151 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Farrell, B, Higgins, M.K. 登録日 2023-07-21 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.945 Å) 主引用文献 PfRH5 bound to monoclonal antibody MAD8-151 To Be Published
8PWU	PfRH5 bound to monoclonal antibody MAD10-255 分子名称: Reticulocyte-binding protein homolog 5, monoclonal antibody MAD10-255 著者 Farrell, B, Higgins, M.K. 登録日 2023-07-21 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.148 Å) 主引用文献 PfRH5 bound to monoclonal antibody MAD10-255 To Be Published
8FHY	Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MALONATE ION, ... 著者 Sankhala, R.S, Jensen, J.L, Joyce, M.G. 登録日 2022-12-15 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques. Nat Commun, 15, 2024

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