6URH

Crystal structure of broadly neutralizing antibody AR3X in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain

Summary for 6URH

Entry DOI	10.2210/pdb6urh/pdb
Descriptor	HCV envelope glycoprotein E2, AR3X Heavy Chain, AR3X Light Chain, ... (9 entities in total)
Functional Keywords	hcv glycoprotein, broadly neutralizing antibodies, viral protein-immune system complex, viral protein/immune system
Biological source	Hepacivirus C More
Total number of polymer chains	3
Total formula weight	83121.19
Authors	Flyak, A.I.,Bjorkman, P.J. (deposition date: 2019-10-23, release date: 2020-03-18, Last modification date: 2023-10-11)
Primary citation	Flyak, A.I.,Ruiz, S.E.,Salas, J.,Rho, S.,Bailey, J.R.,Bjorkman, P.J. An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein. Elife, 9:-, 2020 Cited by PubMed: 32125272 DOI: 10.7554/eLife.53169 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation