4ODT

Fab Structure of lipid A-specific antibody S1-15 in complex with lipid A carbohydrate backbone

Summary for 4ODT

• Entry DOI: 10.2210/pdb4odt/pdb
• Related: 4ODS 4ODU 4ODV 4ODW 4ODY 4ODZ 4OE0
• Descriptor: S1-15 Fab (IgG2b) heavy chain, S1-15 Fab (IgG2b kappa) light chain, 2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: carbohydrate binding, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 49057.19

Authors

Haji-Ghassemi, O.,Evans, S.V. (deposition date: 2014-01-10, release date: 2015-06-24, Last modification date: 2023-09-20)

• Primary citation: Haji-Ghassemi, O.,Muller-Loennies, S.,Rodriguez, T.,Brade, L.,Kosma, P.,Brade, H.,Evans, S.V.; Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA.; J.Biol.Chem., 290:19629-19640, 2015; PubMed: 26085093; DOI: 10.1074/jbc.M115.657874

Experimental method

X-RAY DIFFRACTION (1.95 Å)