PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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4V8R	The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Kalisman, N, Schroder, G.F, Levitt, M. 登録日 2012-03-28 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning Structure, 21, 2013
3NAR	Crystal structure of ZHX1 HD4 (zinc-fingers and homeoboxes protein 1, homeodomain 4) 分子名称: SULFATE ION, Zinc fingers and homeoboxes protein 1 著者 Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF) 登録日 2010-06-02 公開日 2010-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains Bmc Struct.Biol., 10, 2010
4V95	Crystal structure of YAEJ bound to the 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A. 登録日 2012-01-27 公開日 2014-07-09 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science, 335, 2012
4W4G	Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M. 登録日 2014-08-14 公開日 2015-10-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
4V9S	Crystal structure of antibiotic GE82832 bound to 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. 登録日 2013-12-05 公開日 2014-07-09 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
8CK5	VDR LBD complex with 25-nitro derivative of 1,25D3 分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methyl-6-nitro-heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... 著者 Rochel, N. 登録日 2023-02-14 公開日 2023-04-26 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis and biological activities of C25-amino and C25-nitro vitamin D analogs. Bioorg.Chem., 136, 2023
8CKC	Vitamin D receptor complex with 25-amine derivative of 1,25D3 分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-azanyl-6-methyl-heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... 著者 Rochel, N. 登録日 2023-02-15 公開日 2023-04-26 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis and biological activities of C25-amino and C25-nitro vitamin D analogs. Bioorg.Chem., 136, 2023
8C0C	X-ray crystal structure of PPAR gamma ligand binding domain in complex with CZ46 分子名称: (2~{R})-2-[4-(naphthalen-1-ylmethoxy)phenyl]-4-oxidanyl-3-phenyl-2~{H}-furan-5-one, Peroxisome proliferator-activated receptor gamma 著者 Capelli, D, Montanari, R, Pochetti, G, Villa, S, Meneghetti, F. 登録日 2022-12-16 公開日 2023-04-26 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biological Screening and Crystallographic Studies of Hydroxy gamma-Lactone Derivatives to Investigate PPAR gamma Phosphorylation Inhibition. Biomolecules, 13, 2023
9B00	Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with berberine analog of chloramphenicol CAM-BER, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.80A resolution 分子名称: 13-(2-{[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]amino}-2-oxoethyl)-9,10-dimethoxy-5,6-dihydro-2H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Batool, Z, Pavlova, J.A, Paranjpe, M.N, Tereshchenkov, A.G, Lukianov, D.A, Osterman, I.A, Bogdanov, A.A, Sumbatyan, N.V, Polikanov, Y.S. 登録日 2024-03-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. Structure, 2024
4W2F	Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. 登録日 2014-09-12 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol.Cell, 56, 2014
8CBR	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BDM-2 分子名称: (2S)-2-[3-cyclopropyl-2-(3,4-dihydro-2H-chromen-6-yl)-6-methyl-phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
4V9N	Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. 分子名称: 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F. 登録日 2013-04-26 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2. Structure, 21, 2013
5LZT	Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
8CBU	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT884 分子名称: (2S)-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2H-chromen-6-yl)phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
8CBV	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT916 分子名称: (2~{S})-2-[3-cyclopropyl-2-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
4V6F	Elongation complex of the 70S ribosome with three tRNAs and mRNA. 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ... 著者 Jenner, L.B, Yusupova, G, Yusupov, M. 登録日 2009-07-09 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat.Struct.Mol.Biol., 17, 2010
8CBT	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT872 分子名称: (2~{S})-2-[3-cyclopropyl-2-(3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
8CBS	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT871 分子名称: (2~{S})-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
5LZV	Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
4W2G	Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. 登録日 2014-09-12 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol.Cell, 56, 2014
5LZS	Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B 分子名称: (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5LZW	Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
1K74	The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides. 分子名称: (9cis)-retinoic acid, 2-(1-METHYL-3-OXO-3-PHENYL-PROPYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, Peroxisome proliferator activated receptor gamma, ... 著者 Xu, H.E, Lambert, M.H, Montana, V.G, Moore, L.B, Collins, J.L, Oplinger, J.A, Kliewer, S.A, Gampe Jr, R.T, McKee, D.D, Moore, J.T, Willson, T.M. 登録日 2001-10-18 公開日 2001-12-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc.Natl.Acad.Sci.USA, 98, 2001
1K7L	The 2.5 Angstrom resolution crystal structure of the human PPARalpha ligand binding domain bound with GW409544 and a co-activator peptide. 分子名称: 2-(1-METHYL-3-OXO-3-PHENYL-PROPYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, Peroxisome proliferator activated receptor alpha, YTTRIUM (III) ION, ... 著者 Xu, H.E, Lambert, M.H, Montana, V.G, Moore, L.B, Collins, J.L, Oplinger, J.A, Kliewer, S.A, Gampe Jr, R.T, McKee, D.D, Moore, J.T, Willson, T.M. 登録日 2001-10-19 公開日 2001-12-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc.Natl.Acad.Sci.USA, 98, 2001
3NFC	Crystal structure of E.coli MazF Toxin 分子名称: PemK-like protein 1 著者 Wang, X, Wang, K, Su, X, Zhang, J. 登録日 2010-06-10 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and Structural Analysis of E. coli MazF Toxin To be Published

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