Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

This is a large structure.

Summary for 5LZS

EMDB information4130
DescriptoruL2, uL3, uL4, ... (89 entities in total)
Functional Keywordstranslation, elongation, ribosome
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains86
Total molecular weight3496475.49
Shao, S.,Murray, J.,Brown, A.,Taunton, J.,Ramakrishnan, V.,Hegde, R.S. (deposition date: 2016-10-02, release date: 2016-11-30, Last modification date: 2019-12-11)
Primary citation
Shao, S.,Murray, J.,Brown, A.,Taunton, J.,Ramakrishnan, V.,Hegde, R.S.
Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167:1229-1240.e15, 2016
PubMed: 27863242 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2016.10.046
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone3 0.5% 6.6% 0.47MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload