5LZS

Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

This is a large structure.

Summary for 5LZS

EMDB information4130
DescriptoruL2, uL3, uL4, ... (89 entities in total)
Functional Keywordstranslation, elongation, ribosome
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains86
Total molecular weight3496475.49
Authors
Shao, S.,Murray, J.,Brown, A.,Taunton, J.,Ramakrishnan, V.,Hegde, R.S. (deposition date: 2016-10-02, release date: 2016-11-30, Last modification date: 2018-10-17)
Primary citation
Shao, S.,Murray, J.,Brown, A.,Taunton, J.,Ramakrishnan, V.,Hegde, R.S.
Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167:1229-1240.e15, 2016
PubMed: 27863242 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2016.10.046
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (3.31 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone3 0.5% 6.6% 0.47MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5lzs
no rotation
Molmil generated image of 5lzs
rotated about x axis by 90°
Molmil generated image of 5lzs
rotated about y axis by 90°