PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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8Z61	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-18 公開日 2024-05-08 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
8WBL	Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] complexed with sulfate ions 分子名称: Epoxide hydrolase, SULFATE ION 著者 Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. 登録日 2023-09-10 公開日 2024-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
9BRA	Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles 分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... 著者 Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. 登録日 2024-05-11 公開日 2024-06-19 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
8WIZ	cryo-EM structure of alligator haemoglobin in deoxy form 分子名称: BICARBONATE ION, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. 登録日 2023-09-25 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
8VQW	Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (CoA bound) 分子名称: Betaine aldehyde dehydrogenase, CHLORIDE ION, COENZYME A, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-01-19 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (CoA bound) To be published
9CWL	Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Francisella philomiragia (monoclinic P Form) 分子名称: Outer membrane lipocarrier LolA family protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-07-29 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Francisella philomiragia (monoclinic P Form) To be published
9CPL	The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the 2TEL crystallization chaperone via a 2-glycine linker 分子名称: 2TEL/Non-receptor tyrosine-protein kinase TNK1 fusion protein, FORMIC ACID 著者 Samarawickrama, P, Averett, J, Doukov, T, Moody, J.D. 登録日 2024-07-18 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 1TEL Fusions Outperform 2TEL and 3TEL Fusions in Controlled Comparisons To Be Published
9F1S	Structure of UP1 S4ES6E phosphomimetic mutant 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-20 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
8WQC	cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1 分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... 著者 Chen, X, Zhang, K, Xu, C. 登録日 2023-10-11 公開日 2024-04-03 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
8WTX	Cryo-EM structure of noradrenaline transporter in complex with bupropion 分子名称: (2~{R})-2-(~{tert}-butylamino)-1-(3-chlorophenyl)propan-1-one, Sodium-dependent noradrenaline transporter 著者 Zhao, Y, Hu, T, Yu, Z. 登録日 2023-10-19 公開日 2024-08-07 最終更新日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Transport and inhibition mechanisms of the human noradrenaline transporter. Nature, 2024
8YC0	T cell receptor V delta2 V gamma9 in GDN 分子名称: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... 著者 Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. 登録日 2024-02-17 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
9EPY	Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3330 分子名称: 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... 著者 Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2024-03-20 公開日 2024-05-01 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
8VXE	Structure of p38 alpha (Mitogen-activated protein kinase 14) complexed with inhibitor 6 分子名称: (4M)-4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 14 著者 Blaesse, M, Steinbacher, S, Shaffer, P.L, Sharma, S, Thompson, A.A. 登録日 2024-02-04 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions. Acs Med.Chem.Lett., 15, 2024
9ENJ	L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with L-glutamate 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLUTAMIC ACID, L-amino acid oxidase 4, ... 著者 Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H. 登録日 2024-03-13 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure and enzyme engineering of the broad substrate spectrum L-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum to be published
8W2L	TRPM7 structure in complex with anticancer agent CCT128930 in closed state 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ... 著者 Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2024-02-20 公開日 2024-04-17 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Rep, 43, 2024
8VD9	Crystal structure of Bacillus subtilis FabHA, beta-ketoacyl carrier protein synthase III 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-ketoacyl-[acyl-carrier-protein] synthase III 1 著者 Radka, C.D, Rock, C.O. 登録日 2023-12-14 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis. J.Struct.Biol., 216, 2024
8W0D	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor 分子名称: 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-02-13 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor To be published
8VTN	Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-nitrophenylalanine 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... 著者 Tran, K, Mathews, I, Boxer, S.G. 登録日 2024-01-26 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-nitrophenylalanine To Be Published
9F9K	Crystal structure of MUS81-EME1 bound by compound 15. 分子名称: 5-oxidanyl-6-oxidanylidene-2-(4-phenylphenyl)-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... 著者 Collie, G.W. 登録日 2024-05-07 公開日 2024-07-03 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.728 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors. Acs Med.Chem.Lett., 15, 2024
8VDB	Crystal structure of Bacillus subtilis FabHB, beta-ketoacyl carrier protein synthase III 分子名称: Beta-ketoacyl-[acyl-carrier-protein] synthase III 2, GLYCEROL 著者 Radka, C.D, Rock, C.O. 登録日 2023-12-14 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis. J.Struct.Biol., 216, 2024
9GAW	High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. 登録日 2024-07-29 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
8VII	EgtB-IV from Crocosphaera subtropica, an ergothioneine-biosynthetic type IV sulfoxide synthase in complex with cysteine and hercynine 分子名称: 1,2-ETHANEDIOL, CYSTEINE, MANGANESE (II) ION, ... 著者 Ireland, K.A, Davis, K.M. 登録日 2024-01-04 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.621 Å) 主引用文献 Structural insights into the convergent evolution of type IV sulfoxide synthase EgtB, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA Structure, 2024
8W15	HTT in complex with HAP40 in the apo state. 分子名称: 40-kDa huntingtin-associated protein, Huntingtin 著者 Poweleit, N, Boudet, J, Doherty, E. 登録日 2024-02-15 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 Discovery of a Small Molecule Ligand to the Huntingtin/HAP40 complex To Be Published
9AZZ	Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Ehrlichia ruminantium 分子名称: GLYCEROL, Outer membrane lipoprotein carrier protein LolA, TETRAETHYLENE GLYCOL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-03-11 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Ehrlichia ruminantium To be published
8WJ0	cryo-EM structure of human haemoglobin in carbonmonoxy form 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. 登録日 2023-09-25 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024

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