3T26
| Orthorhombic trypsin (bovine) in the presence of sarcosine | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | 登録日 | 2011-07-22 | 公開日 | 2011-12-28 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
|
|
5FZR
| |
5FZS
| |
4Y6C
| Q17M crystal structure of Podosopora anserina putative kinesin light chain nearly identical TPR-like repeats | 分子名称: | ANSERINA PUTATIVE KINESIN LIGHT chain, SULFATE ION | 著者 | Marold, J.D, Kavran, J.M, Bowman, G.D, Barrick, D. | 登録日 | 2015-02-12 | 公開日 | 2015-10-07 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.772 Å) | 主引用文献 | A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins. Structure, 23, 2015
|
|
1SEP
| MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND SEPIAPTERIN | 分子名称: | BIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SEPIAPTERIN REDUCTASE | 著者 | Auerbach, G, Herrmann, A, Guetlich, M, Fischer, M, Jacob, U, Bacher, A, Huber, R. | 登録日 | 1997-05-23 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J., 16, 1997
|
|
2YNE
| Plasmodium vivax N-myristoyltransferase in complex with a benzothiophene inhibitor | 分子名称: | 2-(3-piperidin-4-yloxy-1-benzothiophen-2-yl)-5-[(1,3,5-trimethylpyrazol-4-yl)methyl]-1,3,4-oxadiazole, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | 著者 | Wright, M.H, Clough, B, Rackham, M.D, Brannigan, J.A, Grainger, M, Bottrill, A.R, Heal, W.P, Broncel, M, Serwa, R.A, Mann, D, Leatherbarrow, R.J, Wilkinson, A.J, Holder, A.A, Tate, E.W. | 登録日 | 2012-10-13 | 公開日 | 2014-01-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Validation of N-Myristoyltransferase as an Antimalarial Drug Target Using an Integrated Chemical Biology Approach. Nat.Chem., 6, 2014
|
|
4YPD
| Crystal Structure of DAPK1 catalytic domain in complex with the hinge binding fragment 4-methylpyridazine | 分子名称: | 4-methylpyridazine, CHLORIDE ION, Death-associated protein kinase 1, ... | 著者 | Grum-Tokars, V.L, Minasov, G, Roy, S.M, Anderson, W.F, Watterson, D.M. | 登録日 | 2015-03-12 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of DAPK1 catalytic domain in complex with hinge binding fragments To Be Published
|
|
3ONM
| Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis | 分子名称: | Transcriptional regulator LrhA | 著者 | Quade, N, Diekmann, M, Haffke, M, Heroven, A.K, Dersch, P, Heinz, D.W. | 登録日 | 2010-08-30 | 公開日 | 2011-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis. Acta Crystallogr.,Sect.D, 67, 2011
|
|
5CD1
| Structure of an asymmetric tetramer of human tRNA m1A58 methyltransferase in a complex with SAH and tRNA3Lys | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A, ... | 著者 | Finer-Moore, J, Czudnochowski, N, O'Connell III, J.D, Wang, A.L, Stroud, R.M. | 登録日 | 2015-07-02 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. J.Mol.Biol., 427, 2015
|
|
3L2U
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and GS9137 (Elvitegravir) | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', 6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
|
|
5TMN
| Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues | 分子名称: | CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ... | 著者 | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | 登録日 | 1987-06-29 | 公開日 | 1989-01-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues. Biochemistry, 26, 1987
|
|
5GKZ
| Structure of RyR1 in a closed state (C3 conformer) | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | 著者 | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | 登録日 | 2016-07-07 | 公開日 | 2016-08-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening Cell Res., 26, 2016
|
|
5GSX
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-2 | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-06-07 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5TUD
| Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody | 分子名称: | 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562 chimera, Anti-5-HT2B Fab heavy chain, Anti-5-HT2B Fab light chain, ... | 著者 | Ishchenko, A, Wacker, D, Kapoor, M, Zhang, A, Han, G.W, Basu, S, Boutet, S, James, D, Wang, D, Weierstall, U, Liu, W, Katritch, V, Stevens, R.C, Cherezov, V. | 登録日 | 2016-11-05 | 公開日 | 2017-07-26 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4Y6W
| |
7UQN
| Pathogenesis related 10-10 noscapine complex | 分子名称: | Pathogenesis Related 10-10 protein, noscapine | 著者 | Carr, S.C, Ng, K.K.S. | 登録日 | 2022-04-19 | 公開日 | 2023-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation. Nat Commun, 13, 2022
|
|
5U96
| |
4YS9
| |
7UVP
| |
3P8U
| |
3L2V
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir) | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
|
|
3P5Q
| Ferric R-state human aquomethemoglobin | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Yi, J, Thomas, L.M, Richter-Addo, G.B. | 登録日 | 2010-10-10 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of human R-state aquomethemoglobin at 2.0 A resolution Acta Crystallogr.,Sect.F, 67, 2011
|
|
3H7Y
| Crystal structure of BacB, an enzyme involved in Bacilysin synthesis, in tetragonal form | 分子名称: | 3-PHENYLPYRUVIC ACID, Bacilysin biosynthesis protein bacB, COBALT (II) ION, ... | 著者 | Rajavel, M, Gopal, B. | 登録日 | 2009-04-28 | 公開日 | 2009-09-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Role of Bacillus subtilis BacB in the synthesis of bacilysin J.Biol.Chem., 284, 2009
|
|
5GX8
| Crystal structure of solute-binding protein related to glycosaminoglycans | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, D(-)-TARTARIC ACID, ... | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | 登録日 | 2016-09-15 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.778 Å) | 主引用文献 | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans Sci Rep, 7, 2017
|
|
3L61
| Crystal structure of substrate-free P450cam at 200 mM [K+] | 分子名称: | Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lee, Y.-T, Wilson, R.F, Rupniewski, I, Goodin, D.B. | 登録日 | 2009-12-22 | 公開日 | 2010-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | P450cam visits an open conformation in the absence of substrate. Biochemistry, 49, 2010
|
|