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2YNE

Plasmodium vivax N-myristoyltransferase in complex with a benzothiophene inhibitor

Summary for 2YNE
Entry DOI10.2210/pdb2yne/pdb
Related2YNC 2YND 4A95 4B10 4B11 4B12 4B13 4B14 4BBH
DescriptorGLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, DIMETHYL SULFOXIDE, 2-oxopentadecyl-CoA, ... (8 entities in total)
Functional Keywordstransferase, myristoylation, malaria
Biological sourcePLASMODIUM VIVAX
Total number of polymer chains3
Total formula weight139630.74
Authors
Primary citationWright, M.H.,Clough, B.,Rackham, M.D.,Rangachari, K.,Brannigan, J.A.,Grainger, M.,Moss, D.K.,Bottrill, A.R.,Heal, W.P.,Broncel, M.,Serwa, R.A.,Brady, D.,Mann, D.,Leatherbarrow, R.J.,Tewari, R.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.
Validation of N-Myristoyltransferase as an Antimalarial Drug Target Using an Integrated Chemical Biology Approach.
Nat.Chem., 6:112-, 2014
Cited by
PubMed: 24451586
DOI: 10.1038/NCHEM.1836
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.72 Å)
Structure validation

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