4A95
Plasmodium vivax N-myristoyltransferase with quinoline inhibitor
Summary for 4A95
| Entry DOI | 10.2210/pdb4a95/pdb |
| Descriptor | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, 3-(3-BUTYL-6-METHOXY-2-METHYL-QUINOLIN-4-YL)SULFANYLPROPANENITRILE, 2-oxopentadecyl-CoA, ... (7 entities in total) |
| Functional Keywords | transferase, malaria |
| Biological source | PLASMODIUM VIVAX |
| Total number of polymer chains | 3 |
| Total formula weight | 139033.63 |
| Authors | Goncalves, V.,Brannigan, J.A.,Whalley, D.,Ansell, K.H.,Saxty, B.,Holder, A.A.,Wilkinson, A.J.,Tate, E.W.,Leatherbarrow, R.J. (deposition date: 2011-11-24, release date: 2012-06-27, Last modification date: 2012-07-18) |
| Primary citation | Goncalves, V.,Brannigan, J.A.,Whalley, D.,Ansell, K.H.,Saxty, B.,Holder, A.A.,Wilkinson, A.J.,Tate, E.W.,Leatherbarrow, R.J. Discovery of Plasmodium Vivax N-Myristoyltransferase Inhibitors: Screening, Synthesis, and Structural Characterization of Their Binding Mode. J.Med.Chem., 55:3578-, 2012 Cited by PubMed: 22439843DOI: 10.1021/JM300040P PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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