PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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8SJK	Pembrolizumab Caffeine crystal 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY HEAVY CHAIN, ANTIBODY LIGHT CHAIN, ... 著者 Larpent, P, Codan, L, Bothe, J.R, Stueber, D, Reichert, P, Fischmann, T, Su, Y, Pabit, S, Gupta, S, Iuzzolino, L, Cote, A. 登録日 2023-04-18 公開日 2024-04-24 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Small-Angle X-ray Scattering as a Powerful Tool for Phase and Crystallinity Assessment of Monoclonal Antibody Crystallites in Support of Batch Crystallization. Mol Pharm., 2024
6XCA	Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105 分子名称: C105 Heavy Chain, C105 Light Chain, SULFATE ION 著者 Sharaf, N.G, Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
7JMX	Crystal structure of a SARS-CoV-2 cross-neutralizing antibody COVA1-16 Fab 分子名称: ACETATE ION, COVA1-16 heavy chain, COVA1-16 light chain, ... 著者 Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. 登録日 2020-08-03 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53, 2020
6B5N	Structure of PfCSP peptide 25 with human protective antibody CIS43 分子名称: CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP 著者 Pancera, M, Weidle, C. 登録日 2017-09-29 公開日 2018-03-21 最終更新日 2018-04-25 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
1YED	STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.4) 分子名称: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG1 FAB FRAGMENT (D.2.4) 著者 Golinelli-Pimpaneau, B, Knossow, M. 登録日 1997-04-15 公開日 1997-10-15 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural convergence in the active sites of a family of catalytic antibodies. Science, 275, 1997
1YEE	STRUCTURE OF A CATALYTIC ANTIBODY, IGG2A FAB FRAGMENT (D2.5) 分子名称: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG2A FAB FRAGMENT (D2.5) 著者 Golinelli-Pimpaneau, B, Knossow, M. 登録日 1997-04-15 公開日 1997-10-15 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural convergence in the active sites of a family of catalytic antibodies. Science, 275, 1997
7JMW	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... 著者 Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. 登録日 2020-08-03 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53, 2020
2YMX	Crystal structure of inhibitory anti-AChE Fab408 分子名称: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN, GLYCEROL 著者 Bourne, Y, Renault, L, Essono, S, Mondielli, G, Lamourette, P, Bocquet, D, Grassi, J, Marchot, P. 登録日 2012-10-10 公開日 2013-10-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region Plos One, 8, 2013
7E3O	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody nCoV617 分子名称: Spike protein S1, nCoV617 Heigh Chain, nCoV617 Light Chain 著者 Chen, S.D, Yang, M. 登録日 2021-02-09 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural Basis of a Human Neutralizing Antibody Specific to the SARS-CoV-2 Spike Protein Receptor-Binding Domain. Microbiol Spectr, 9, 2021
3PP4	Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies 分子名称: B-lymphocyte antigen CD20, CHLORIDE ION, GA101 Fab heavy chain, ... 著者 Hopfner, K.-P, Lammens, A. 登録日 2010-11-24 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. Blood, 118, 2011
3PP3	Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies 分子名称: GA101 Fab heavy chain, GA101 Fab light chain 著者 Hopfner, K.-P, Lammens, A. 登録日 2010-11-24 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.508 Å) 主引用文献 Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. Blood, 118, 2011
1YEC	STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.3) 分子名称: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG2A FAB FRAGMENT (D2.3), ZINC ION 著者 Golinelli-Pimpaneau, B, Knossow, M. 登録日 1997-04-15 公開日 1997-10-15 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural convergence in the active sites of a family of catalytic antibodies. Science, 275, 1997
6B5M	Structure of PfCSP peptide 21 with human protective antibody CIS43 分子名称: 1,2-ETHANEDIOL, CIS43 Fab Heavy chain, CIS43 Fab Light chain, ... 著者 Pancera, M, Weidle, C. 登録日 2017-09-29 公開日 2018-03-21 最終更新日 2018-04-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
5VGP	Fc fragment of human IgG1 antibody, from NIST mAb 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Human Fc fragment with G1F/G0F glycan, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Gallagher, D.T, Galvin, C.V, Karageorgos, I, Marino, J.P. 登録日 2017-04-11 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.116 Å) 主引用文献 Structure of the Fc fragment of the NIST reference antibody RM8671. Acta Crystallogr F Struct Biol Commun, 74, 2018
6CXC	3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Envelope glycoprotein chimera, ... 著者 Xie, Q, Wang, Z, Chen, X, Ni, F, Ma, J, Wang, Q. 登録日 2018-04-02 公開日 2019-07-31 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein. Plos One, 14, 2019
6DC7	Apo Fab structure of mouse monoclonal antibody 8B2 分子名称: Fab heavy chain, Fab light chain 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
6DCA	Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. 分子名称: Fab heavy chain, Fab light chain, Microtubule-associated protein tau, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.599 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
6DC9	Fab/epitope complex of human chimeric monoclonal antibody h4E6 targeting a phosphorylated tau epitope. 分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
6DC8	Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope. 分子名称: GLYCEROL, IgG heavy chain, IgG light chain, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
6UM5	Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Acharya, P, Henderson, R.C, Saunders, K.O, Haynes, B.F. 登録日 2019-10-09 公開日 2019-12-18 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
7R40	Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 87G7 heavy chain variable region, ... 著者 Hurdiss, D.L. 登録日 2022-02-08 公開日 2022-04-20 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern. Sci Immunol, 7, 2022
4PLJ	Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12 分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein 著者 Tang, X.H, Li, S.W, Sivaraman, J. 登録日 2014-05-18 公開日 2015-04-15 最終更新日 2015-05-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody Cell Res., 25, 2015
5I0Z	Crystal structure of the single domain catalytic antibody 3D8-VH 分子名称: catalytic DNA antibody 著者 Park, S.Y, Kim, J.S. 登録日 2016-02-04 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the single domain catalytic antibody 3D8-VH To Be Published
6UM7	Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH270.mu1 Fab Heavy Chain, DH270.mu1 Fab Light chain, ... 著者 Acharya, P, Henderson, R.C, Saunders, K, Haynes, B.F. 登録日 2019-10-09 公開日 2019-12-18 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
8DPM	Structure of EBOV GP lacking the mucin-like domain with 9.20.1A2 Fab and 6D6 scFv bound 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 6D6 scFv, Antibody 9.20.1A2 Fab heavy chain, ... 著者 Yu, X, Saphire, E.O. 登録日 2022-07-15 公開日 2023-07-19 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus. Cell Rep, 42, 2023

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