6DC8
Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope.
Summary for 6DC8
| Entry DOI | 10.2210/pdb6dc8/pdb |
| Descriptor | IgG light chain, IgG heavy chain, Microtubule-associated protein tau, ... (6 entities in total) |
| Functional Keywords | monoclonal antibody, fab, tau, phosphorylation state -specific antibody, immune system |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 3 |
| Total formula weight | 51308.86 |
| Authors | Chukwu, J.E.,Kong, X.-P. (deposition date: 2018-05-04, release date: 2019-03-20, Last modification date: 2019-12-18) |
| Primary citation | Chukwu, J.E.,Congdon, E.E.,Sigurdsson, E.M.,Kong, X.P. Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11:477-488, 2019 Cited by PubMed: 30794086DOI: 10.1080/19420862.2019.1574530 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.799 Å) |
Structure validation
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