6DC8
Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | IgG light chain | polymer | 218 | 24237.7 | 1 | Mus musculus (mouse) | ||
| 2 | B (H) | IgG heavy chain | polymer | 217 | 23431.2 | 1 | Mus musculus (mouse) | ||
| 3 | C (P) | Microtubule-associated protein tau | polymer | 31 | 3268.6 | 1 | UniProt (P10636) | Homo sapiens | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
| 4 | D, E, F (L, H) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G (P) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | H, I, J (L, H, P) | water | water | 18.0 | 569 | Chemie (HOH) |
Sequence modifications
P: 379 - 408 (UniProt: P10636)
| PDB | External Database | Details |
|---|---|---|
| Nh2 409 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50937.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 371.3 | |
| All* | Total formula weight | 51308.9 |
