6DC8

Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope.

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue GOL L 301

Chain	Residue
L	LEU37
L	LYS39
L	GLU45
L	GLU81
L	ASP82
L	HOH403
L	HOH526

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL H 301

Chain	Residue
H	ASN98
H	HOH486
L	TYR49
L	PHE55
L	ASP151
P	PO4501
H	ARG96
H	ASP97

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL H 302

Chain	Residue
H	PRO119
H	VAL121
H	THR204
H	LYS208

---

site_id	AC4
Number of Residues	8
Details	binding site for residue PO4 P 501

Chain	Residue
H	GOL301
L	TYR32
L	LYS50
L	HIS189
L	HOH412
P	SER404
P	HIS407
P	HOH601

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by CK1 and PDPK1","evidences":[{"source":"PubMed","id":"14761950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15546861","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19451179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21327254","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9614189","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"15546861","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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