6DCA
Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope.
Summary for 6DCA
Entry DOI | 10.2210/pdb6dca/pdb |
Descriptor | Fab light chain, Fab heavy chain, Microtubule-associated protein tau, ... (5 entities in total) |
Functional Keywords | monoclonal antibody, fab, tau, phosphorylation state-specific antibody, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 204764.04 |
Authors | Chukwu, J.E.,Kong, X.-P. (deposition date: 2018-05-04, release date: 2019-03-20, Last modification date: 2019-12-18) |
Primary citation | Chukwu, J.E.,Congdon, E.E.,Sigurdsson, E.M.,Kong, X.P. Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11:477-488, 2019 Cited by PubMed: 30794086DOI: 10.1080/19420862.2019.1574530 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.599 Å) |
Structure validation
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