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6DCA

Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope.

Summary for 6DCA
Entry DOI10.2210/pdb6dca/pdb
DescriptorFab light chain, Fab heavy chain, Microtubule-associated protein tau, ... (5 entities in total)
Functional Keywordsmonoclonal antibody, fab, tau, phosphorylation state-specific antibody, immune system
Biological sourceMus musculus (mouse)
More
Total number of polymer chains12
Total formula weight204764.04
Authors
Chukwu, J.E.,Kong, X.-P. (deposition date: 2018-05-04, release date: 2019-03-20, Last modification date: 2019-12-18)
Primary citationChukwu, J.E.,Congdon, E.E.,Sigurdsson, E.M.,Kong, X.P.
Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein.
MAbs, 11:477-488, 2019
Cited by
PubMed: 30794086
DOI: 10.1080/19420862.2019.1574530
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.599 Å)
Structure validation

217705

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