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6DCA

Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D, G, J
(L, M, N, O)
Fab light chainpolymer21823982.74Mus musculus (mouse)
2B, E, H, K
(H, I, J, K)
Fab heavy chainpolymer22123844.74Mus musculus (mouse)
3C, F, I, L
(P, Q, R, S)
Microtubule-associated protein taupolymer313268.64UniProt (P10636)Homo sapiensNeurofibrillary tangle protein,Paired helical filament-tau,PHF-tau
4M, N, O, P
(L, M, R, S)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
5AA, Q, R, S, T...
(S, L, H, P, M...)
waterwater18.0302Chemie (HOH)
Sequence modifications
P, Q, R, S: 379 - 408 (UniProt: P10636)
PDBExternal DatabaseDetails
Nh2 409-amidation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight204384.2
Non-Polymers*Number of molecules4
Total formula weight379.9
All*Total formula weight204764.0
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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