3PP3
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
Summary for 3PP3
| Entry DOI | 10.2210/pdb3pp3/pdb |
| Related | 3PP4 |
| Descriptor | GA101 Fab heavy chain, GA101 Fab light chain (3 entities in total) |
| Functional Keywords | antibody fab-fragment ig-domain, antibody, cd20, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 4 |
| Total formula weight | 95869.41 |
| Authors | Hopfner, K.-P.,Lammens, A. (deposition date: 2010-11-24, release date: 2011-04-13, Last modification date: 2023-09-06) |
| Primary citation | Niederfellner, G.,Lammens, A.,Mundigl, O.,Georges, G.J.,Schaefer, W.,Schwaiger, M.,Franke, A.,Wiechmann, K.,Jenewein, S.,Slootstra, J.W.,Timmerman, P.,Brannstrom, A.,Lindstrom, F.,Mossner, E.,Umana, P.,Hopfner, K.P.,Klein, C. Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. Blood, 118:358-367, 2011 Cited by PubMed: 21444918DOI: 10.1182/blood-2010-09-305847 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.508 Å) |
Structure validation
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