5VGP

Fc fragment of human IgG1 antibody, from NIST mAb

Summary for 5VGP

• Entry DOI: 10.2210/pdb5vgp/pdb
• Related: 5K8A
• Descriptor: Human Fc fragment with G1F/G0F glycan, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: human, antibody, glycoform, g1f/g0f, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 53347.83

Authors

Gallagher, D.T.,Galvin, C.V.,Karageorgos, I.,Marino, J.P. (deposition date: 2017-04-11, release date: 2018-04-18, Last modification date: 2023-10-04)

• Primary citation: Gallagher, D.T.,Galvin, C.V.,Karageorgos, I.; Structure of the Fc fragment of the NIST reference antibody RM8671.; Acta Crystallogr F Struct Biol Commun, 74:524-529, 2018; PubMed: 30198883; DOI: 10.1107/S2053230X18009834

Experimental method

X-RAY DIFFRACTION (2.116 Å)