2YMX

Crystal structure of inhibitory anti-AChE Fab408

Summary for 2YMX

• Entry DOI: 10.2210/pdb2ymx/pdb
• Descriptor: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN, GLYCEROL, ... (4 entities in total)
• Functional Keywords: immune system, acetylcholinesterase, inhibition, back door region
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 2
• Total formula weight: 47798.98

Authors

Bourne, Y.,Renault, L.,Essono, S.,Mondielli, G.,Lamourette, P.,Bocquet, D.,Grassi, J.,Marchot, P. (deposition date: 2012-10-10, release date: 2013-10-23, Last modification date: 2023-12-20)

• Primary citation: Bourne, Y.,Renault, L.,Essono, S.,Mondielli, G.,Lamourette, P.,Boquet, D.,Grassi, J.,Marchot, P.; Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region; Plos One, 8:77266-, 2013; PubMed: 24146971; DOI: 10.1371/JOURNAL.PONE.0077226

Experimental method

X-RAY DIFFRACTION (1.9 Å)