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8C6A
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Light SFX structure of D.m(6-4)photolyase at 1ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
8C6B
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Light SFX structure of D.m(6-4)photolyase at 20ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
8C6F
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Light SFX structure of D.m(6-4)photolyase at 400fs time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
8C2F
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Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5
分子名称: 14-3-3 protein sigma, ARG-ALA-HIS-SEP-CYS-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ...
著者van den Oetelaar, M.C.M, Ottmann, C.
登録日2022-12-22
公開日2023-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A simple method for developing lysine targeted covalent protein reagents.
Nat Commun, 14, 2023
7UE1
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HIV-1 Integrase Catalytic Core Domain Mutant (KGD) in Complex with Inhibitor GRL-142
分子名称: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, Integrase, SULFATE ION
著者Aoki, M, Aoki-Ogata, H, Bulut, H, Hayashi, H, Davis, D, Hasegawa, K, Yarchoan, R, Ghosh, A.K, Pau, A.K, Mitsuya, H.
登録日2022-03-21
公開日2023-03-22
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Sci Adv, 9, 2023
5AGQ
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Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes
分子名称: BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A
著者Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M.
登録日2015-02-03
公開日2015-05-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
5A7R
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Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J.
登録日2015-07-09
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase.
J.Am.Chem.Soc., 137, 2015
8DGF
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Avs4 bound to phage PhiV-1 portal
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding protein Avs4, MAGNESIUM ION, ...
著者Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F.
登録日2022-06-23
公開日2022-08-03
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
Science, 377, 2022
4ZXQ
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P22 Tail Needle Gp26 1-140 crystallized at pH 3.9
分子名称: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
著者Sankhala, R.S, Cingolani, G.
登録日2015-05-20
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
8CRG
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E. coli adenylate kinase in complex with two ADP molecules as a result of enzymatic AP4A hydrolysis
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase
著者Oelker, M, Tischlik, S, Wolf-Watz, M, Sauer-Eriksson, A.E.
登録日2023-03-08
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Insights into Enzymatic Catalysis from Binding and Hydrolysis of Diadenosine Tetraphosphate by E. coli Adenylate Kinase.
Biochemistry, 62, 2023
5BON
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BU of 5bon by Molmil
Crystal structure of human Nudt15 (MTH2)
分子名称: MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15
著者Carter, M, Jemth, A.-S, Helleday, T, Stenmark, P.
登録日2015-05-27
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.
Nat Commun, 6, 2015
8E1I
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Asp1 kinase in complex with ATP Mg 5-IP7
分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, ADENOSINE-5'-TRIPHOSPHATE, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase, ...
著者Goldgur, Y, Shuman, S, Benjamin, B.
登録日2022-08-10
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.
Mbio, 13, 2022
8E5T
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Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
著者Sanghai, Z.A, Piwowarczyk, R, Vanden Broeck, A, Klinge, S.
登録日2022-08-22
公開日2023-04-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation.
Nat.Struct.Mol.Biol., 30, 2023
8EB7
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Cryo-EM structure of the in-situ gp4-gp10-gp9N from bacteriophage P22
分子名称: Packaged DNA stabilization protein gp10, Peptidoglycan hydrolase gp4, Tail spike protein
著者Wang, C, Liu, J, Molineux, I.J.
登録日2022-08-30
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献In-situ structure of tail machine reveals mechanistic insights into P22 assembly
To Be Published
1Y98
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Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
著者Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2004-12-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
6I8T
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THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR
分子名称: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1
著者Casale, E, Papeo, G, Montagnoli, A.
登録日2018-11-21
公開日2019-05-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
Acs Med.Chem.Lett., 10, 2019
1WFQ
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Solution structure of the first cold-shock domain of the human KIAA0885 protein (UNR protein)
分子名称: UNR protein
著者Goroncy, A.K, Kigawa, T, Koshiba, S, Tomizawa, T, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-26
公開日2004-11-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein.
J.Struct.Funct.Genom., 11, 2010
6J0D
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Crystal structure of OsSUF4
分子名称: ZINC ION, transcription factor
著者Wang, B, Luo, Q.
登録日2018-12-24
公開日2019-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment.
Nat Commun, 10, 2019
6J0W
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Crystal Structure of Yeast Rtt107 and Nse6
分子名称: Peptide from DNA repair protein KRE29, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
5CNV
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Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
登録日2015-07-18
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
2RS7
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Solution structure of the second dsRBD from RNA helicase A
分子名称: ATP-dependent RNA helicase A
著者Nagata, T, Muto, Y, Tsuda, K, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-11-29
公開日2012-03-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structures of the double-stranded RNA-binding domains from RNA helicase A
Proteins, 80, 2012
2RS6
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Solution structure of the N-terminal dsRBD from RNA helicase A
分子名称: ATP-dependent RNA helicase A
著者Nagata, T, Muto, Y, Tsuda, K, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-11-29
公開日2012-03-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structures of the double-stranded RNA-binding domains from RNA helicase A
Proteins, 80, 2012
6H4C
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, NICKEL (II) ION, ...
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
6JCF
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Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron
分子名称: CACODYLATE ION, Integrase
著者Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W.
登録日2019-01-28
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
1YDX
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Crystal structure of Type-I restriction-modification system S subunit from M. genitalium
分子名称: CHLORIDE ION, type I restriction enzyme specificity protein MG438
著者Machado, B, Quijada, O, Pinol, J, Fita, I, Querol, E, Carpena, X.
登録日2004-12-27
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of a Putative Type I Restriction-Modification S Subunit from Mycoplasma genitalium
J.Mol.Biol., 351, 2005

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